Department of Radiology, Vrije Universiteit Brussel, Brussels, Belgium.
Centrum voor Kankeropsporing (Centre for Cancer Detection), Brugge, Belgium.
Eur J Public Health. 2023 Dec 9;33(6):1122-1127. doi: 10.1093/eurpub/ckad137.
Pre-scheduled appointments can increase attendance in breast cancer screening programmes compared to 'open invitations' but relatively few randomized controlled trials exist. We investigated the effect of a pre-scheduled appointment on uptake in the Flemish population-based mammography screening programme.
Between September and December 2022, a total of 4798 women were randomly assigned to receive either a pre-scheduled appointment or open invitation. The difference in attendance was compared with Poisson regression analysis for the primary endpoint (attendance ≤92 days after date of invitation), yielding relative risks (RRs). This was done separately for three groups: women invited to a mobile unit and a history of nonattendance (group M-NA); women invited to a hospital-based unit and a history of nonattendance (group HB-NA); women invited to a hospital-based unit and a history of irregular attendance (group HB-IA). There were no women invited to a mobile unit and a history of irregular attendance.
The RRs in favour of the pre-scheduled appointment were 2.3 [95% confidence interval (CI) 1.80-2.88], 1.8 (95% CI 1.07-2.97) and 1.8 (95% CI 1.43-2.39), for groups M-NA, HB-NA and HB-IA, respectively. We found no statistically significant difference between the various RRs. The respective absolute gains in attendance between pre-scheduled appointment and open invitation were 8.3%, 4.4% and 15.8%.
Sending an invitation with a pre-scheduled appointment is an effective tool to increase screening attendance in both mobile and hospital-based screening units. The pre-scheduled appointment is associated with a considerable absolute gain in attendance which varies depending on the screening history.
与“开放式邀请”相比，预约可以提高乳腺癌筛查计划的参与度，但随机对照试验相对较少。我们研究了预约对弗拉芒人群为基础的乳房 X 光筛查计划参与度的影响。
在 2022 年 9 月至 12 月期间，共有 4798 名女性被随机分配接受预约或开放式邀请。采用泊松回归分析比较主要终点（邀请后 92 天内的参与度）的差异，得出相对风险（RR）。这分别在三组中进行：既往未参与且受邀至移动单位的女性（组 M-NA）；既往未参与且受邀至医院单位的女性（组 HB-NA）；既往不规则参与且受邀至医院单位的女性（组 HB-IA）。没有受邀至移动单位且既往不规则参与的女性。
预约对 M-NA、HB-NA 和 HB-IA 组的有利相对风险分别为 2.3（95%置信区间 [CI]：1.80-2.88）、1.8（95% CI：1.07-2.97）和 1.8（95% CI：1.43-2.39）。我们没有发现这些相对风险之间存在统计学上的显著差异。与开放式邀请相比，预约的参与度分别增加了 8.3%、4.4%和 15.8%。
发送带有预约的邀请是提高移动和医院筛查单位参与度的有效工具。预约与参与度的显著增加有关，这种增加幅度取决于筛查史。
