Fitzsimmons W E
Drug Intell Clin Pharm. 1986 Jul-Aug;20(7-8):538-42. doi: 10.1177/106002808602000703.
The interpretation of serum digoxin concentrations is an area where pharmacists can have substantial clinical input. Important in this interpretation is the knowledge of various factors that may interfere with the reported concentration. These include drugs, metabolites of digoxin, protein concentration, and endogenous digoxin-like substances. The patients for whom these interferences are most significant include neonates, patients with renal failure and liver disease, and pregnant women. Pharmacist knowledge of these interferences can have an important impact on the quality of patient care.
血清地高辛浓度的解读是一个药剂师可提供大量临床意见的领域。解读时，了解各种可能干扰报告浓度的因素很重要。这些因素包括药物、地高辛代谢物、蛋白质浓度和内源性地高辛样物质。这些干扰最为显著的患者包括新生儿、肾衰竭和肝病患者以及孕妇。药剂师对这些干扰因素的了解会对患者护理质量产生重要影响。
