高通量双目模式视网膜电图在小鼠中的应用。
High-Throughput Binocular Pattern Electroretinograms in the Mouse.
机构信息
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
JORVEC Corp, Miami, FL, USA.
出版信息
Methods Mol Biol. 2023;2708:147-153. doi: 10.1007/978-1-0716-3409-7_16.
The pattern electroretinogram (PERG) reflects the electrical activity of retinal ganglion cells (RGC) and has become the most used technology to assess RGC function in experimental models of glaucoma and optic neuropathies. We describe a novel method for obtaining user-friendly, robust PERG simultaneously from each eye using asynchronous binocular stimulation and one-channel acquisition of signals recorded from a subcutaneous needle in the snout.
图形视网膜电图 (PERG) 反映了视网膜神经节细胞 (RGC) 的电活动，已成为评估青光眼和视神经病变实验模型中 RGC 功能的最常用技术。我们描述了一种新颖的方法，使用异步双眼刺激和从鼻部皮下针记录的信号的单通道采集，同时从每只眼睛获得用户友好、稳健的 PERG。
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