Department of Geriatrics Medicine, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha, China.
Department of Radiology, Xiangya Hospital, Central South University, Changsha, China.
J Clin Hypertens (Greenwich). 2023 Sep;25(9):853-860. doi: 10.1111/jch.14706. Epub 2023 Aug 9.
The celiac ganglion (CG) is associated with the sympathetic nervous system (SNS) and plays an important role in the pathogenesis of hypertension. The characteristics of the CG in patients with hypertension remain unknown. The aim of our study was to explore the differences in celiac ganglia (CGs) characteristics between hypertensive and non-hypertensive populations using computed tomography (CT). CGs manifestations on multidetector row CT in 1003 patients with and without hypertension were retrospectively analyzed. The morphological characteristics and CT values of the left CGs were recorded. The CT values of the ipsilateral adrenal gland (AG) and crus of the diaphragm (CD) were also measured. The left CG was located between the left AG and CD, and most CGs were long strips. The frequency of visualization of the left CGs was higher in the hypertension group than in the non-hypertension group (p < .05). There were no significant differences in the maximum diameter, size, and shape ratio of the left CGs between the two groups (p > .05). Except for the left CG in the arterial phase, the CT values of the left CG and AG in the non-hypertensive group were higher than those in the hypertension group (p < .05). The venous phase enhancement of the left CG in the non-hypertension group was significantly higher than that in the hypertension group (p < .05). Our findings reveal that CGs have characteristic manifestations in the hypertensive population. As important targets of the SNS, CGs have the potential to regulate blood pressure.
腹腔神经节(CG)与交感神经系统(SNS)有关,在高血压的发病机制中起重要作用。高血压患者 CG 的特征尚不清楚。我们的研究旨在使用计算机断层扫描(CT)探讨高血压和非高血压人群 CG 特征的差异。回顾性分析了 1003 例高血压和非高血压患者 CT 多排螺旋 CT 上 CG 的形态特征和 CT 值。记录左侧 CG 的形态特征和 CT 值。还测量了同侧肾上腺(AG)和膈肌(CD)的 CT 值。左侧 CG 位于左侧 AG 和 CD 之间,大多数 CG 呈长条状。高血压组左侧 CG 的显示频率高于非高血压组(p<.05)。两组间左侧 CG 的最大直径、大小和形状比无显著性差异(p>.05)。除了动脉期左侧 CG 外,非高血压组左侧 CG 和 AG 的 CT 值均高于高血压组(p<.05)。非高血压组左侧 CG 的静脉期强化明显高于高血压组(p<.05)。我们的研究结果表明,CG 在高血压人群中有特征性表现。作为 SNS 的重要靶点,CG 具有调节血压的潜力。