Ahmed Shajeda, Tran Quoc Vinh, McLean Mary
Emergency Medicine, Ross University School of Medicine, Bridgetown, BRB.
Emergency Medicine, AdventHealth East Orlando, Orlando, USA.
Cureus. 2023 Aug 8;15(8):e43144. doi: 10.7759/cureus.43144. eCollection 2023 Aug.
Kratom () is an herb that is sold over the counter in both pill and liquid forms. It contains opioid and stimulant properties and is used for relaxation as well as for weaning off opioid addictions. While a few adverse effects of kratom have been already reported, mainly with concerns around its toxicity, very little is known about it. We report a case of a female in her 40s presenting with signs of hypoxia reversed with naloxone administration, initially suspected to be a case of opioid overdose. Upon becoming alert and oriented, the patient and her husband reported that she consumed a large amount of kratom bought from the local gas station, and he later noticed that her lips were turning blue and she was becoming increasingly altered. Her urine toxicology was noted to be negative for opioids or any other substance use. The patient survived this accidental overdose due to the quick action of her husband, who rushed her to the emergency department (ED) upon realizing she appeared altered and very ill. It is important for emergency medicine practitioners to be aware of kratom overdose as a possible item on the differential diagnosis. This paper focuses on kratom overdose presentation and treatment.
kratom（）是一种草药，有药丸和液体两种形式在柜台出售。它具有阿片类药物和兴奋剂特性，用于放松以及戒除阿片类药物成瘾。虽然已经报告了 kratom 的一些不良反应，主要是关于其毒性，但人们对它的了解非常少。我们报告了一例 40 多岁女性的病例，该患者出现缺氧症状，经注射纳洛酮后症状缓解，最初怀疑是阿片类药物过量。在患者恢复清醒并定向后，患者及其丈夫报告说她服用了从当地加油站购买的大量 kratom，随后他注意到她的嘴唇变蓝，且她的意识状态越来越差。她的尿液毒理学检测显示阿片类药物或任何其他物质使用呈阴性。由于她丈夫的迅速行动，患者在这次意外过量服用后幸存下来，她丈夫在意识到她出现意识改变且病情严重后，立即将她送往了急诊科（ED）。对于急诊医学从业者来说，意识到 kratom 过量是鉴别诊断中可能出现的情况很重要。本文重点关注 kratom 过量的表现和治疗。
