心肌桥和壁冠状动脉中CTA表现与心功能指标之间的关系。
The relationship between CTA performances and cardiac function indicators in myocardial bridge and mural coronary artery.
作者信息
Guo Fuzhen, Yan Junfen, Xue Xiubin
机构信息
Department of Emergency, The First Hospital of Zhangjiakou Zhangjiakou 075000, Hebei, China.
Department of Gastroenterology, Hebei Huaao Hospital Zhangjiakou 075000, Hebei, China.
出版信息
Am J Transl Res. 2023 Jul 15;15(7):4779-4787. eCollection 2023.
OBJECTIVE
To investigate the relationship between computed tomography angiography (CTA) performances and cardiac function indicators in patients with myocardial bridge and mural coronary artery (MB-MCA).
METHODS
The clinical data of 60 patients with MB-MCA receiving CTA in the First Hospital of Zhangjiakou from January 2021 to February 2022 were analyzed retrospectively. The patients were divided into different groups based on CTA performances, including the degree of stenosis of the left anterior descending (LAD) MCA, whether there was atherosclerosis in the anterior segment of MB of LAD branch, the MB thickness, and the degree of stenosis of the LAD branch. The correlation between these TCA performances and cardiac function indicators including end-systolic volume (ESV), end-diastolic volume (EDV), stroke volume (SV), cardiac output (CO), and left ventricular ejection fraction (LVEF) was analyzed. Besides, the receiver operating characteristic (ROC) curve was used to analyze the predictive performance of cardiac function indicators for the severity of MB-MCA.
RESULTS
ESV, EDV, SV, CO and LVEF were statistically different between the moderate stenosis group and mild stenosis group (all P < 0.05). EDV, SV, CO, and LVEF were statistically different between the atherosclerosis group and non-atherosclerosis group (all P < 0.05). SV, CO, LVEF in the deep group were lower than that in the superficial group (all P < 0.05). EDV, CO, LVEF were different between the LAD moderate stenosis group and LAD mild stenosis group (all P < 0.05). The AUC (areas under the curve) of combined detection of ESV, EDV, SV, CO, and LVEF in predicting the severity of MB-MCA was 0.907, which was higher than the single indicator predictive effect.
CONCLUSIONS
Cardiac function indicators, mainly CO and LVEF are correlated with the CTA performance of MB-MCA patients. The combination of cardiac function indicators has a good effect in predicting the severity of MB-MCA.
目的
探讨心肌桥合并壁冠状动脉（MB-MCA）患者的计算机断层血管造影（CTA）表现与心功能指标之间的关系。
方法
回顾性分析2021年1月至2022年2月在张家口市第一医院接受CTA检查的60例MB-MCA患者的临床资料。根据CTA表现将患者分为不同组，包括左前降支（LAD）MCA的狭窄程度、LAD分支MB前段是否存在动脉粥样硬化、MB厚度以及LAD分支的狭窄程度。分析这些CTA表现与心功能指标（包括收缩末期容积（ESV）、舒张末期容积（EDV）、每搏输出量（SV）、心输出量（CO）和左心室射血分数（LVEF））之间的相关性。此外，采用受试者操作特征（ROC）曲线分析心功能指标对MB-MCA严重程度的预测性能。
结果
中度狭窄组与轻度狭窄组的ESV、EDV、SV、CO和LVEF差异有统计学意义（均P<0.05）。动脉粥样硬化组与非动脉粥样硬化组的EDV、SV、CO和LVEF差异有统计学意义（均P<0.05）。深层组的SV、CO、LVEF低于浅层组（均P<0.05）。LAD中度狭窄组与LAD轻度狭窄组的EDV、CO、LVEF不同（均P<0.05）。ESV、EDV、SV、CO和LVEF联合检测预测MB-MCA严重程度的曲线下面积（AUC）为0.907，高于单一指标的预测效果。
结论
心功能指标，主要是CO和LVEF与MB-MCA患者的CTA表现相关。心功能指标联合应用对预测MB-MCA的严重程度有良好效果。
Zotero 插件