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创伤后应激障碍退伍军人失眠的临床特征:确定使用镇静催眠药进行诊断和治疗的风险因素。

Clinical Characterization of Insomnia among Veterans with PTSD: Identifying Risk Factors for Diagnosis and Treatment with Sedative-Hypnotics.

作者信息

Bramoweth Adam D, Luther James, Hanusa Barbara H, Walker Jon D, Atwood Charles W, Germain Anne

机构信息

Mental Illness Research, Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.

Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.

出版信息

Def Peace Econ. 2017 Jul 12;29. doi: 10.1080/10242694.2017.1349633.

Abstract

Insomnia is prevalent among Veterans with post-traumatic stress disorder (PTSD), it exacerbates PTSD symptoms, and it contributes to impaired functioning and quality of life. To improve treatment outcomes, it is important to identify risk factors for insomnia and sedative-hypnotic use. Classification and regression trees and logistic regression models were used to identify variables associated with insomnia or sedative-hypnotic use. Key findings include low insomnia diagnosis rates (3.5-5.6%) and high rates of sedative-hypnotics (44.2-49.0%). Younger Veterans and those without a breathing-related sleep disorder (BRSD) were more likely to receive an insomnia diagnosis. Veterans with greater service connection and those with an alcohol/substance use disorder were more likely to be prescribed sedative-hypnotics. Interaction terms may have identified potential groups at risk of being under-diagnosed with insomnia (i.e. non-black Veterans with psychiatric co-morbidity, black Veterans without psychiatric co-morbidity) as well as groups at risk for sedative-hypnotic use (i.e. younger Veterans without BRSD). In sum, Veterans with PTSD have high rates of sedative-hypnotic use despite minimal evidence they are effective. This is counter to recommendations indicating behavioral interventions are the first-line treatment. Policy changes are needed to reduce use of sedative-hypnotics and increase access to behavioral insomnia interventions.

摘要

失眠在患有创伤后应激障碍(PTSD)的退伍军人中很普遍,它会加剧PTSD症状,并导致功能受损和生活质量下降。为了改善治疗效果,识别失眠和使用镇静催眠药的风险因素很重要。使用分类回归树和逻辑回归模型来识别与失眠或使用镇静催眠药相关的变量。主要发现包括失眠诊断率低(3.5 - 5.6%)和镇静催眠药使用率高(44.2 - 49.0%)。年轻的退伍军人和没有呼吸相关睡眠障碍(BRSD)的人更有可能被诊断为失眠。服役关联度更高的退伍军人和患有酒精/物质使用障碍的人更有可能被开处方使用镇静催眠药。交互项可能已经确定了有失眠诊断不足风险的潜在群体(即患有精神共病的非黑人退伍军人、没有精神共病的黑人退伍军人)以及有使用镇静催眠药风险的群体(即没有BRSD的年轻退伍军人)。总之,患有PTSD的退伍军人使用镇静催眠药的比例很高,尽管几乎没有证据表明它们有效。这与表明行为干预是一线治疗方法的建议背道而驰。需要改变政策以减少镇静催眠药的使用,并增加获得行为性失眠干预措施的机会。

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