甲状腺肿瘤的预后因素
Prognostic factors in thyroid tumours.
作者信息
Kerr D J, Burt A D, Boyle P, MacFarlane G J, Storer A M, Brewin T B
出版信息
Br J Cancer. 1986 Sep;54(3):475-82. doi: 10.1038/bjc.1986.200.
Abstract
Using Cox's Proportional Hazard Model, we have demonstrated the influence of age, sex, microscopic tumour type, extent of primary tumour, nodal status and the presence of metastases on prognosis, in our population of 441 patients with thyroid carcinoma. The TNM classification contributes significantly to survival, but does not include other contributory prognostic variables, whereas the prognostic index developed by the EORTC thyroid study group, which takes account of age and histology, proved a reliable predictor of survival for our patient group.
摘要
在我们的441例甲状腺癌患者群体中，使用Cox比例风险模型，我们已经证明了年龄、性别、微观肿瘤类型、原发肿瘤范围、淋巴结状态以及转移情况对预后的影响。TNM分类对生存率有显著贡献，但不包括其他有助于判断预后的变量，而欧洲癌症研究与治疗组织（EORTC）甲状腺研究组制定的预后指数，该指数考虑了年龄和组织学因素，被证明是我们患者群体生存率的可靠预测指标。
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