Department of Organic and Medicinal Chemistry, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Kolkata-700032, WB, India.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India.
J Med Chem. 2023 Aug 24;66(16):10868-10877. doi: 10.1021/acs.jmedchem.3c01304. Epub 2023 Aug 10.
The present publication provides a comprehensive look at more than a decade (2010 to midyear of 2023) of medicinal chemistry research in India, focusing on contributions to medicinal chemistry and drug discovery from both Indian academia and industries. The work provides an overview of cutting-edge medicinal chemistry research along with the organic-transformation-based chemical research scenarios in India in the past decade. It also distinguishes areas of research as well as contributions from different federal research institutes, state universities, central universities, and private universities by their geographical locations around India. The paper takes broader stock of the situation by comparing the articles published in the two internationally acclaimed journals in the field, viz. , which highlights the current research trends as well as the thrust needed at the grass-roots level to boost medicinal chemistry and drug discovery research in India. Finally, we believe that this discussion may create a pathway for policymakers and funding agencies to focus their efforts to motivate lesser inclined institutions as well as provide incentives to the institutions primarily involved in medicinal chemistry research, as they already have built capacity for such research.
本出版物全面回顾了十余年（2010 年至 2023 年年中）的印度药物化学研究，重点介绍了印度学术界和工业界在药物化学和药物发现方面的贡献。该工作概述了过去十年中印度前沿药物化学研究以及基于有机转化的化学研究情况。它还根据印度各地的地理位置，区分了不同联邦研究机构、邦立大学、中央大学和私立大学的研究领域和贡献。本文通过比较该领域两个享有国际盛誉的期刊发表的文章，更广泛地了解了情况，突出了当前的研究趋势以及在基层推动印度药物化学和药物发现研究所需的推动力。最后，我们相信，这一讨论可能为政策制定者和资助机构提供一条途径，集中精力激励不太倾向于开展研究的机构，并为主要从事药物化学研究的机构提供激励，因为它们已经具备了开展此类研究的能力。
