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[琥珀酸在神经元对突触激活反应中的作用]

[The role of succinic acid in neuron reaction to synaptic activation].

作者信息

Sergeeva S S, Bazanova I S, Burgova M P, Kondrashova M N

出版信息

Biofizika. 1986 Jul-Aug;31(4):631-3.

PMID:3756230
Abstract

It has been shown on Retzius neuron of the leech that after preintroduction of sodium succinate the reaction to synaptic stimulation expressed in increased frequency of the impulse activity proceeds more intensively than in the norm. In connection with the fact that against the background of succinate effect reaction to acetylcholine increases it is suggested that this very mediator is responsible for slower decrease of the impulse activity frequency at synaptic activation.

摘要

已经发现,在水蛭的雷丘斯神经元上,预先引入琥珀酸钠后,由冲动活动频率增加所表示的对突触刺激的反应比正常情况下进行得更强烈。鉴于在琥珀酸盐作用的背景下对乙酰胆碱的反应增强这一事实,有人提出正是这种介质导致了突触激活时冲动活动频率下降得更慢。

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