发育中小鼠大脑中酸性和碱性磷酸酶活性的变化。
Changes of acid and alkaline phosphatase activities in the developing mouse brain.
作者信息
Ng T B, Tam P P
出版信息
Biol Neonate. 1986;50(2):107-13. doi: 10.1159/000242575.
PMID:3756257
Abstract
Acid and alkaline phosphatase activities in the mouse cerebrum, brainstem and cerebellum increased during the late fetal and perinatal period and reached a maximum on postnatal day 28 (P28). Myelination was most extensive on P28-P45 in the brainstem and in the cerebellum, and phosphatidic acid phosphatase activity concomitantly decreased to a low level after birth. The changes in acid and alkaline phosphatase activities correlate more with the extent of myelination than with the overall brain tissue growth.
摘要
在小鼠的大脑、脑干和小脑中，酸性和碱性磷酸酶活性在胎儿后期和围产期增加，并在出生后第28天（P28）达到最大值。髓鞘形成在出生后第28天至45天在脑干和小脑中最为广泛，并且磷脂酸磷酸酶活性在出生后随之降低至低水平。酸性和碱性磷酸酶活性的变化与髓鞘形成的程度相关性更大，而不是与整个脑组织的生长相关。
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