Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel.
Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
BMC Pregnancy Childbirth. 2023 Aug 10;23(1):572. doi: 10.1186/s12884-023-05863-4.
Postpartum retained products of conception (RPOC) can cause short- and long-term complications. Diagnosis is based on ultrasound examination and treated with hysteroscopy. This study evaluated the size of RPOC that can be related to a positive pathology result for residua.
This retrospective cohort study included women who underwent hysteroscopy for postpartum RPOC diagnosed by ultrasound, 4/2014-4/2022. Demographics, intrapartum, sonographic, intraoperative, and post-operative data were retrieved. We generated a ROC curve and found 7 mm was the statistically sonographic value for positive pathology for RPOC. Data between women with sonographic RPOC ≤ 7 mm and > 7 mm were compared. Positive and negative predictive values were calculated for RPOC pathology proved which was measured by ultrasound.
Among 212 patients who underwent hysteroscopy due to suspected RPOC on ultrasound, 20 (9.4%) women had residua ≤ 7 mm and 192 (90.6%) had residua > 7 mm. The most common complaint was vaginal bleeding in 128 cases (60.4%); more so in the residua > 7 mm group (62.5% vs. 40%, p = .05). Among women with residua ≤ 7 mm, the interval from delivery to hysteroscopy was longer (117.4 ± 74.7 days vs. 78.8 ± 68.8 days, respectively; p = .02). Positive pathology was more frequent when residua was > 7 mm. PPV for diagnosis of 7 mm RPOC during pathology examination was 75.3% and NPV 50%.
Sonographic evaluation after RPOC showed that residua > 7 mm was statistically correlated with positive RPOC in pathology and PPV of 75% and NPV of 50%. Due to the high NPV and low complication rate of office hysteroscopy, clinicians should consider intervention when any RPOC are measured during sonographic examination to reduce known long-term complications.
产后胎盘残留(RPOC)可导致短期和长期并发症。诊断基于超声检查,并采用宫腔镜治疗。本研究评估了 RPOC 的大小与残留物阳性病理结果相关的可能性。
这是一项回顾性队列研究,纳入了 2014 年 4 月至 2022 年 4 月期间因超声诊断为产后 RPOC 而行宫腔镜检查的女性。提取人口统计学、分娩期、超声、术中及术后数据。我们生成了 ROC 曲线,发现 7mm 是 RPOC 阳性病理的统计学超声值。比较了超声 RPOC≤7mm 和>7mm 的女性数据。计算了经超声测量的 RPOC 病理学证实的阳性和阴性预测值。
在 212 例因超声怀疑 RPOC 而行宫腔镜检查的患者中,20 例(9.4%)女性残留物≤7mm,192 例(90.6%)残留物>7mm。最常见的主诉是阴道出血 128 例(60.4%);残留物>7mm 组更多(62.5%比 40%,p=0.05)。残留物≤7mm 的女性,从分娩到宫腔镜检查的时间间隔更长(分别为 117.4±74.7 天和 78.8±68.8 天;p=0.02)。残留物>7mm 时阳性病理更为常见。7mm RPOC 病理检查的阳性预测值为 75.3%,阴性预测值为 50%。
RPOC 后超声评估显示,残留物>7mm 与病理学上 RPOC 阳性具有统计学相关性,阳性预测值为 75%,阴性预测值为 50%。由于宫腔镜检查的并发症发生率低、阴性预测值高,当超声检查发现任何 RPOC 时,临床医生应考虑干预,以减少已知的长期并发症。