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大鼠脑脉络丛中血清素(5-羟色胺)结合位点的个体发生。

Ontogenesis of serotonin (5-HT) binding sites in the choroid plexus of the rat brain.

作者信息

Zilles K, Rath M, Schleicher A, Glaser T, Traber J

出版信息

Brain Res. 1986 Aug 13;380(1):201-3. doi: 10.1016/0006-8993(86)91450-2.

Abstract

The increase in density of 5-HT1c receptors in the choroid plexus of the third and lateral ventricles was analyzed in rats between the 1st and 90th postnatal days. An increase was found between the 3rd day and the 4th to 5th week, at which time adult values are attained. The development of the 5-HT1c receptors clearly differs from that of 5-HT1 receptors in other brain regions. The density in the choroid plexus is about 20% higher in the third ventricle than in the lateral ventricles.

摘要

分析了出生后第1天至第90天大鼠第三脑室和侧脑室脉络丛中5-羟色胺1c(5-HT1c)受体密度的增加情况。在出生后第3天至第4至5周之间发现有增加,此时达到成年值。5-HT1c受体的发育明显不同于其他脑区的5-HT1受体。第三脑室脉络丛中的密度比侧脑室高约20%。

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