Gupta Divya, Kerai Sukhyanti, Saxena Kirti N, Gaur Saurabh
Department of Anaesthesiology and Intensive Care, Maulana Azad Medical College and Associated Hospitals, New Delhi, India.
J Anaesthesiol Clin Pharmacol. 2023 Apr-Jun;39(2):273-278. doi: 10.4103/joacp.joacp_378_21. Epub 2022 Aug 22.
Several studies have attempted to identify patients at risk of developing severe pain after caesarean section (CS) by utilizing preoperative experimental pain application and clinical tests. The three-item questionnaire and reported pain intensity on infiltration of local anesthetic (LA) on the back of patient just before administration of spinal anesthesia, are two simple tests previously shown to be promising. We aimed to study utility of these two tools in Indian patients undergoing CS and find their correlation with postoperative pain and analgesic consumption.
A total of 150 parturients undergoing elective CS were enrolled. Preoperatively patients were asked to rate their level of anxiety, anticipated postoperative pain and analgesic need after surgery (three-item questionnaire). The pain intensity reported by patient upon LA injection for spinal anesthesia were recorded. In the postoperative period, pain intensity at rest, evoked pain and need for rescue analgesics were recorded. The correlation between three item questionnaire and pain on LA infiltration to postoperative pain were evaluated. To see relationship between the predictor variables to outcome, a multiple regression analysis was performed.
The predictors variables and postoperative pain were found to have mild correlation (r = 0.124 to 0.239). The predictor variables were significantly correlated with postoperative pain at rest but their association was not significant to evoked pain intensity. Multiple regression analysis showed that change in the predictors explains only 7-8% variance in postoperative pain outcomes.
The three -item questionnaire and pain intensity reported upon LA infiltration for spinal anesthesia have mild correlation to postoperative pain in Indian parturients undergoing CS. As these variables predicts only 8% variance in pain experienced after CS, further studies are required for accurate prediction and targeted treatment of post CS pain.
多项研究试图通过术前进行实验性疼痛刺激和临床测试,来识别剖宫产术后发生严重疼痛的风险患者。三项问卷调查以及在蛛网膜下腔麻醉给药前患者背部局部麻醉药浸润时报告的疼痛强度,是之前已显示出前景的两项简单测试。我们旨在研究这两种工具在接受剖宫产的印度患者中的效用,并找出它们与术后疼痛及镇痛药物消耗量的相关性。
共纳入150例接受择期剖宫产的产妇。术前要求患者对焦虑程度、预期术后疼痛及术后镇痛需求进行评分(三项问卷调查)。记录患者在蛛网膜下腔麻醉注射局部麻醉药时报告的疼痛强度。术后记录静息时的疼痛强度、诱发疼痛及急救镇痛药物的需求。评估三项问卷调查结果以及局部麻醉药浸润时的疼痛与术后疼痛之间的相关性。为观察预测变量与结果之间的关系,进行了多元回归分析。
发现预测变量与术后疼痛存在轻度相关性(r = 0.124至0.239)。预测变量与术后静息时的疼痛显著相关,但它们与诱发疼痛强度的关联不显著。多元回归分析表明,预测变量的变化仅能解释术后疼痛结果中7 - 8%的方差。
三项问卷调查以及蛛网膜下腔麻醉注射局部麻醉药时报告的疼痛强度,与接受剖宫产的印度产妇术后疼痛存在轻度相关性。由于这些变量仅能预测剖宫产术后疼痛体验中8%的方差,因此需要进一步研究以准确预测和针对性治疗剖宫产术后疼痛。