Suppr超能文献

自体骨软骨移植治疗膝关节骨软骨疾病在60岁以上患者中可带来良好的患者报告结局。

Autologous Osteochondral Grafts for Knee Osteochondral Diseases Result in Good Patient-Reported Outcomes in Patients Older Than 60 Years.

作者信息

Nakagawa Yasuaki, Mukai Shogo, Satomi Kentaro, Shinya Yuki, Nakamura Ryota, Takahashi Motoi

机构信息

Clinical Research Center, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.

Department of Orthopaedic Surgery, Japan Baptist Medical Foundation, Kyoto, Japan.

出版信息

Arthrosc Sports Med Rehabil. 2023 Jul 26;5(5):100774. doi: 10.1016/j.asmr.2023.100774. eCollection 2023 Oct.

Abstract

PURPOSE

This study aims to examine the clinical autologous osteochondral grafts (AOG) outcomes for knee osteochondral diseases at operative ages >60 years, and to determine whether patients are able to sit straight in Japanese style after AOG.

METHODS

All patients who underwent AOG for knee osteochondral diseases between November 2001 and April 2018 were retrospectively identified. The inclusion criteria were AOG only without osteotomy, operative ages between 60 and 79 years, >2 years of follow-up, and involved femorotibial angle between 169° and 179° (normal alignment). Patients who underwent osteotomy to improve knee alignment and patients with inflammatory diseases such as rheumatoid arthritis were excluded. The patients' knee symptoms and their clinical outcome were evaluated according to the criteria of the knee scoring system of the Japanese Orthopedic Association (JOA), International Knee Documentation Committee (IKDC) subjective score, and the ability of straight sitting in Japanese style.

RESULTS

This study enrolled 57 cases and 60 knee joints during the study period. The follow-up ratio was 85.1%. Moreover, 14 men and 43 women and 29 right and 31 left knee joints were included in this study. The mean operative age and mean follow-up period were 67.8 years (range 60-76 years) and 81.1 months (range 24-167 months), respectively. In addition, the study involved 30 cases and 32 knee joints (60s group), and 27 cases and 28 knee joints (70s group). Moreover, 34 cases and 36 knee joints had osteonecrosis (ON group), and 23 cases and 24 knee joints had cartilage injury (CI group). The IKDC subjective and JOA scores in both the 60s and 70s groups showed significant differences: 2 years after AOG >at the follow-up period, >at the preoperative period. The scores in both the CI and ON groups showed similar significant differences. Furthermore, 8.3% and 53.5% of the patients could sit straight in Japanese style at the preoperative period and 2 years after AOG, respectively.

CONCLUSION

Even if the patient's operative age was >60 years, the AOG only for their knee osteochondral diseases had good clinical outcomes, including the ability to sit straight in Japanese style.

LEVEL OF EVIDENCE

IV, Therapeutic case series Key words: autologous osteochondral grafts, aged patients, clinical outcome, knee joint, straight sitting in Japanese style.

摘要

目的

本研究旨在探讨手术年龄大于60岁的膝部骨软骨疾病患者行临床自体骨软骨移植(AOG)的效果,并确定患者在AOG术后能否采用日式坐姿挺直坐立。

方法

回顾性纳入2001年11月至2018年4月间因膝部骨软骨疾病接受AOG手术的所有患者。纳入标准为仅行AOG而未行截骨术、手术年龄在60至79岁之间、随访时间超过2年且股胫角在169°至179°之间(正常对线)。排除为改善膝关节对线而行截骨术的患者以及患有类风湿关节炎等炎性疾病的患者。根据日本骨科协会(JOA)膝关节评分系统标准、国际膝关节文献委员会(IKDC)主观评分以及日式挺直坐立能力对患者的膝关节症状及其临床结局进行评估。

结果

本研究在研究期间共纳入57例患者及60个膝关节。随访率为85.1%。此外,本研究纳入14例男性和43例女性,以及29个右膝关节和31个左膝关节。平均手术年龄和平均随访时间分别为67.8岁(范围60 - 76岁)和81.1个月(范围24 - 167个月)。另外,本研究包括30例患者及32个膝关节(60多岁组)和27例患者及28个膝关节(70多岁组)。此外,34例患者及36个膝关节患有骨坏死(ON组),23例患者及24个膝关节患有软骨损伤(CI组)。60多岁组和70多岁组的IKDC主观评分和JOA评分均显示出显著差异:AOG术后2年>随访期>术前。CI组和ON组的评分也显示出类似的显著差异。此外,术前和AOG术后2年分别有8.3%和53.5%的患者能够采用日式坐姿挺直坐立。

结论

即使患者手术年龄大于60岁,仅针对其膝部骨软骨疾病进行AOG仍具有良好的临床效果,包括能够采用日式坐姿挺直坐立。

证据级别

IV,治疗性病例系列 关键词:自体骨软骨移植;老年患者;临床结局;膝关节;日式挺直坐立

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24bd/10410132/bf7a26cea43c/gr1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验