Youdim M B, Feldman S C, Pappas G D, Pollard H B
Brain Res. 1986 Sep 3;381(2):300-4. doi: 10.1016/0006-8993(86)90080-6.
Monoamine oxidase activity, using type A and type B substrates and inhibitors, was investigated in the central brain and synaptosomes prepared from the optic lobe of squid. Although substantial MAO activity towards serotonin (5-HT), phenylethylamine and tyramine was present, the enzyme could not be differentiated into the two subtypes previously described in the vertebrate central nervous system. However, this enzyme is functional since 5-HT levels, as identified by immunocytochemical procedures, are low in the squid nervous system and show significant increases in pargyline treated squids.
利用A型和B型底物及抑制剂，对鱿鱼视叶制备的中枢脑和突触体中的单胺氧化酶活性进行了研究。尽管存在对血清素（5 - HT）、苯乙胺和酪胺的大量单胺氧化酶活性，但该酶无法区分为先前在脊椎动物中枢神经系统中描述的两种亚型。然而，这种酶是有功能的，因为通过免疫细胞化学方法鉴定，鱿鱼神经系统中的5 - HT水平较低，且在使用帕吉林处理的鱿鱼中显示出显著升高。
