Department of Rehabilitation Medicine, Showa University School of Medicine, Kanagawa, Japan.
Department of Internal medicine, Sakuragaoka Central Hospital, Kanagawa, Japan.
Medicine (Baltimore). 2023 Aug 11;102(32):e34519. doi: 10.1097/MD.0000000000034519.
Neurosarcoidosis tends to prolong the duration of treatment and may result in a decline in physical function requiring rehabilitation. Because of a rare disease, the adjustment of oral steroid dosage, which is the cornerstone of treatment, is highly dependent on professional experience in general. Therefore, the number of hospitals that can perform dosage adjustment is very limited, and it is difficult to provide concurrent intense rehabilitation at the same hospital over a long period of time, and there are no reports that mention this.
A 49-year-old man, who presented with impaired consciousness, dysphagia and right hemiplegia, was diagnosed with neurosarcoidosis based on a previous diagnosis of sarcoidosis, laboratory test results, and clinical symptoms. High-dose oral steroid therapy was initiated and he was transferred to our rehabilitation hospital for progressive disuse approximately 2 months after the disease onset.
This case was diagnosed as "probable" neurosarcoidosis.
The steroid dose was not reduced during rehabilitation treatment in our hospital considering the risk of relapse of the primary disease due to steroid reduction. His training regimen focused on minimum activities of daily living was performed, and its effectiveness was determined during approximately 60 days after the initiation of rehabilitation.
Two months after admission, he was independently eating, transferring, and toileting under supervision. He was discharged home 3 months after admission.
Intensive rehabilitation can be one of the effective comprehensive treatment strategy for patients with neurosarcoidosis. On the other hand, since there is no consensus treatment method, the duration of rehabilitation and goal setting should be adjusted based on an understanding of the characteristics of the disease and the overall treatment plan.
神经结节病往往会延长治疗时间,并可能导致身体功能下降,需要康复。由于是一种罕见疾病,治疗的基石——口服类固醇剂量的调整高度依赖于一般的专业经验。因此,能够进行剂量调整的医院数量非常有限,并且很难在同一医院长时间提供同步强化康复,并且没有报道提到这一点。
一名 49 岁男性,因意识障碍、吞咽困难和右侧偏瘫就诊,根据先前的结节病诊断、实验室检查结果和临床症状诊断为神经结节病。发病约 2 个月后,给予大剂量口服类固醇治疗,因疾病进展导致废用,转入我院康复医院。
该病例被诊断为“可能”神经结节病。
考虑到原发性疾病因类固醇减少而复发的风险,在我院康复治疗期间未减少类固醇剂量。他的训练方案侧重于进行最低限度的日常生活活动,在康复开始后大约 60 天确定其效果。
入院后 2 个月,他在监督下能够独立进食、转移和上厕所。入院后 3 个月出院回家。
强化康复可以是神经结节病患者的有效综合治疗策略之一。另一方面,由于没有共识的治疗方法,应根据对疾病特征和整体治疗计划的了解,调整康复时间和目标设定。