Nguyen Austin Q, Harvey Jackson P, Federico Vincent P, Nolte Michael T, Khanna Krishn, Gandhi Sapan D, Sheha Evan D, Colman Matthew W, Phillips Frank M
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Department of Orthopedics and Sports Medicine, Houston Methodist Hospital, Houston, TX, USA.
Global Spine J. 2025 Jan;15(1):112-120. doi: 10.1177/21925682231195777. Epub 2023 Aug 11.
Retrospective Cohort Study.
Restoration of lordosis in lumbar fusion reduces low back pain, decreases adjacent segment degeneration, and improves postoperative outcomes. However, the potential effects of changes in segmental lordosis on adjacent-level and global lordosis remain less understood. This study aims to examine the relationships between segmental (SL), adjacent-level, and global lumbar lordosis following L5-S1 Anterior Lumbar Interbody Fusion (ALIF).
80 consecutive patients who underwent single-level L5-S1 ALIF were divided into 3 groups based on the degree of change (∆) in index-level segmental lordosis: <5° (n = 23), 5°-10° (n = 29), >10° (n = 28). Radiographic parameters measured included global lumbar, segmental, and adjacent level lordosis, sacral slope, pelvic tilt, pelvic incidence, and PI-LL mismatch.
Patients with ∆SL 5°-10° or ∆SL >10° both showed significant increases in global lumbar lordosis from preoperative to final follow-up. However, patients with ∆SL >10° showed statistically significant losses in adjacent level lordosis at both immediate postoperative and final follow-up compared to preoperative. When comparing patients with ∆SL >10° to those with ∆SL 5-10°, there were no significant differences in global lumbar lordosis at final follow-up, due to significantly greater losses of adjacent level lordosis in these patients.
The degree of compensatory loss of lordosis at the adjacent level L4-L5 correlated with the extent of segmental lordosis creation at the index L5-S1 level. This may suggest that the L4 to S1 segment acts as a "harmonious unit," able to accommodate only a certain amount of lordosis and further increases in segmental lordosis may be mitigated by loss of adjacent-level lordosis.
回顾性队列研究。
腰椎融合术中恢复前凸可减轻腰痛,减少相邻节段退变,并改善术后结果。然而,节段性前凸变化对相邻节段和整体前凸的潜在影响仍鲜为人知。本研究旨在探讨L5-S1前路腰椎椎间融合术(ALIF)后节段性(SL)、相邻节段和整体腰椎前凸之间的关系。
80例连续接受单节段L5-S1 ALIF的患者根据索引节段性前凸的变化程度(∆)分为3组:<5°(n = 23)、5°-10°(n = 29)、>10°(n = 28)。测量的影像学参数包括整体腰椎、节段性和相邻节段前凸、骶骨倾斜度、骨盆倾斜度、骨盆入射角和PI-LL失配。
∆SL为5°-10°或∆SL>10°的患者从术前到最终随访时整体腰椎前凸均显著增加。然而,与术前相比,∆SL>10°的患者在术后即刻和最终随访时相邻节段前凸均有统计学意义的丢失。将∆SL>10°的患者与∆SL为5-10°的患者进行比较时,最终随访时整体腰椎前凸无显著差异,因为这些患者相邻节段前凸的丢失明显更大。
L4-L5相邻节段前凸的代偿性丢失程度与索引L5-S1节段节段性前凸的形成程度相关。这可能表明L4至S1节段作为一个“和谐单元”,只能容纳一定量的前凸,节段性前凸的进一步增加可能会因相邻节段前凸的丢失而减轻。