Department of Translational and Precision Medicine, Sapienza University of Rome, Viale Dell'Università 37, 00185, Rome, Italy.
Department of Clinical Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Viale Dell'Università 37, 00185, Rome, Italy.
Intern Emerg Med. 2024 Apr;19(3):757-760. doi: 10.1007/s11739-023-03390-w. Epub 2023 Aug 11.
There is still little information regarding the long-term safety of the vaccines. We report a case of new-onset adult-onset Still's disease (AOSD) that occurred following Covid-19 vaccination. This patient went to the emergency room with dyspnea from the last two weeks and bilateral swellings that occurred several weeks after the first vaccination. Based on the symptoms and laboratory results, we suspected AOSD. Considering the time relationship between Covid-19 vaccination and AOSD onset in our patient, and possible mechanisms linking vaccination with the onset of autoimmune disorders, physicians should consider adverse events from Covid-19 vaccination and assess the benefits and risks of vaccination for each patient.
关于疫苗的长期安全性,目前信息仍然较少。我们报告了一例新冠疫苗接种后新发成人Still 病(AOSD)。该患者因两周前出现呼吸困难和双侧肿胀,于首剂疫苗接种后数周来院就诊。根据症状和实验室结果,我们怀疑为 AOSD。考虑到该患者新冠疫苗接种与 AOSD 发病之间的时间关系,以及疫苗接种与自身免疫性疾病发病之间可能存在的机制,医生应考虑新冠疫苗接种的不良事件,并评估每位患者接种疫苗的获益和风险。