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[塞内尔-厄舍综合征(脂溢性天疱疮):一个特殊病例]

[Senear-Usher syndrome (seborrheic pemphigus): An exceptional case].

作者信息

Galán-Lozano Juan David, Velasco-Castro Julio César, García-Agudelo Lorena, Vargas-Rodríguez Ledmar Jovanny

机构信息

Departamento de Investigación, Hospital Regional de la Orinoquía, Yopal, Casanare, Colombia.

出版信息

Rev Alerg Mex. 2023 Jun 28;70(2):102-106. doi: 10.29262/ram.v70i2.1223.

Abstract

BACKGROUND

Among the autoimmune diseases causing erosive lesions and blisters on skin and mucous membranes is pemphigus. Within this is a rare subtype known as seborrheic pemphigus or Senear-usher syndrome which is characterized by broken blisters and crusts involving the seborrheic areas.

CASE REPORT

A 40-year-old female patient, initially treated in a first level unit for a condition of 45 days of evolution, characterized by thick scabby lesions with an erythematous base, pruritic and painful, located in the center of the face, with posterior extension towards the abdomen, thorax, and extremities. Treatment consisted of prednisolone, with favorable evolution. The biopsy of the lesions with the diagnosis of seborrheic pemphigus.

CONCLUSIONS

Senear-usher syndrome is a rare disease of multifactorial origin. Early diagnosis and adequate treatment are decisive factors to avoid the evolution and advanced forms of the disease.

摘要

背景

天疱疮是导致皮肤和黏膜出现糜烂性病变及水疱的自身免疫性疾病之一。其中有一种罕见的亚型,称为脂溢性天疱疮或塞内尔-厄舍综合征,其特征是水疱破裂和结痂,累及脂溢部位。

病例报告

一名40岁女性患者,最初在一级医疗机构接受治疗,病程45天,其特征为面部中央出现厚痂性病变,基底呈红斑状,伴有瘙痒和疼痛,并向后延伸至腹部、胸部和四肢。治疗采用泼尼松龙,病情好转。病变活检诊断为脂溢性天疱疮。

结论

塞内尔-厄舍综合征是一种多因素起源的罕见疾病。早期诊断和适当治疗是避免疾病进展和晚期形式的决定性因素。

相似文献

3
[A case of seborrheic pemphigoid (Senear-Usher syndrome)].
Arch Belg Dermatol Syphiligr. 1951 Sep;7(3):208-13.
6
[Senear-Usher syndrome and pemphigus].
Arch Klin Exp Dermatol. 1955;200:211-5.
7
[Subseborrheic pemphigus; Senear-Usher syndrome?].
Bull Soc Fr Dermatol Syphiligr. 1951 May-Jun;58(3):289-91.
10
A case for diagnosis: Senear-Usher syndrome?
AMA Arch Derm Syphilol. 1951 Oct;64(4):525-6.

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