氟甲酰胺未能控制牛精液中的脲原体。
The failure of flurofamide to control ureaplasma in bovine semen.
作者信息
Truscott R B, Brown C
出版信息
Can J Vet Res. 1986 Apr;50(2):289-90.
The flurofamide sensitivities of 21 bovine ureaplasma isolates were determined using the metabolic inhibition method. The 21 isolates included seven each of vaginal, preputial and seminal origin. The minimum inhibitory concentrations of flurofamide ranged from 0.0125 to 0.2 meg/mL against a ureaplasma titer of 10(4) organisms/mL. The minimum lethal concentrations ranged from less than or equal to 0.1 to 3.2 mcg/mL. Flurofamide was then evaluated in a system comparable to the procedure for semen extension with respect to temperature, time and dilution. The compound was found to be ineffective in reducing ureaplasma numbers in this system at levels up to 1500 mcg/mL.
采用代谢抑制法测定了21株牛脲原体分离株对氟洛米特的敏感性。这21株分离株包括来自阴道、包皮和精液的各7株。氟洛米特对10⁴个/mL脲原体滴度的最低抑菌浓度范围为0.0125至0.2μg/mL。最低致死浓度范围为≤0.1至3.2μg/mL。然后在与精液稀释程序相当的系统中，就温度、时间和稀释度对氟洛米特进行了评估。结果发现，在该系统中，该化合物在高达1500μg/mL的水平下对减少脲原体数量无效。
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