Clamp J R, Fairclough P D
Clin Chim Acta. 1986 Aug 30;159(1):69-71. doi: 10.1016/0009-8981(86)90167-1.
A study has been made of the gastric secretions from a patient with Zollinger-Ellison syndrome without peptic ulceration, before and after treatment with cimetidine. The amount of non-diffusable glycoconjugates was measured as an index of mucin output, and found to be within normal limits. Cimetidine, which greatly reduced the volume of secretions, had no effect on the non-diffusable glycoconjugates. These results may explain the absence of peptic ulceration in certain patients with this syndrome.
对一名无消化性溃疡的佐林格-埃利森综合征患者在使用西咪替丁治疗前后的胃分泌物进行了研究。将不可扩散糖缀合物的量作为粘蛋白分泌量的指标进行测量，发现其在正常范围内。西咪替丁虽然大大减少了分泌量，但对不可扩散糖缀合物没有影响。这些结果可能解释了该综合征某些患者无消化性溃疡的原因。
