Yenimahalle Education and Training Hospital, Yıldırım Beyazıt University, Ankara 06900, Turkey.
Department of Ophthalmology, Baskent University, Ankara, Turkey.
Photodiagnosis Photodyn Ther. 2023 Dec;44:103741. doi: 10.1016/j.pdpdt.2023.103741. Epub 2023 Aug 11.
The aim of this study was to examine if choroidal vascularity index (CVI) is different in eyes with unilateral vitreomacular traction (VMT) from their healthy fellow eyes; and whether different treatments affect the CVI.
The baseline and 8-week post treatment CVIs of 56 unilateral VMT patients that underwent spontaneous resolution (n = 30), vitreoretinal surgery (n = 16) or pneumatic vitreolysis (n = 10) were compared with fellow eyes using paired samples t-test. Partial correlation analyses correcting age and gender was used for calculations between treatment groups. P values < 0.05 were considered statistically significant.
The mean baseline CVI for VMT and control eyes had no statistically significant difference (p = 0.81, r= -0.38). The post traction release follow-up CVI of VMT eyes and contralateral eyes had no significant difference (p = 0.12, r = 0.49). In spontaneous resolution group, vitreoretinal surgery group and pneumatic vitreolysis group the baseline and follow up CVIs of VMT eyes were statistically similar (p = 0.72, p = 0.32 and p = 0.79 respectively).Spontaneous detachment patients' CVIs showed a 0.57±5.81% increase, vitreoretinal surgery group had a reduction of 1.098±4.76%, and the pneumatic vitreolysis patients showed a CVI reduction of 0.307±4.24%. However, none of these changes was found to be statistically significant when compared between the groups (p = 0.21, r = 0.02).
Previous studies have argued that vitreomacular traction might have a role on the choroidal changes seen in the vitreoretinal interface disorders. This study has shown that VMT alone does not cause any significant changes in choroidal vascular index pre or post traction release.
本研究旨在探讨单侧玻璃体黄斑牵引（VMT）患眼与对侧正常眼的脉络膜血管指数（CVI）是否不同；以及不同治疗方法是否会影响 CVI。
对 56 例单侧 VMT 患者（自发缓解组 n=30 例，玻璃体视网膜手术组 n=16 例，气动玻璃体切除术组 n=10 例）进行基线和 8 周治疗后 CVI 测量，并与对侧眼进行配对样本 t 检验比较。采用偏相关分析校正年龄和性别，比较治疗组之间的相关性。P 值<0.05 为统计学显著差异。
VMT 眼和对照眼的基线 CVI 无统计学差异（p=0.81，r=-0.38）。牵引松解后 VMT 眼和对侧眼的 CVI 无显著差异（p=0.12，r=0.49）。在自发缓解组、玻璃体视网膜手术组和气动玻璃体切除术组中，VMT 眼的基线和随访 CVI 无统计学差异（p=0.72，p=0.32 和 p=0.79 分别）。自发脱离患者的 CVI 增加了 0.57±5.81%，玻璃体视网膜手术组降低了 1.098±4.76%，气动玻璃体切除术组降低了 0.307±4.24%。然而，当组间比较时，这些变化均无统计学意义（p=0.21，r=0.02）。
既往研究认为玻璃体黄斑牵引可能在玻璃体视网膜界面疾病中引起脉络膜变化。本研究表明，VMT 本身在牵引松解前后不会引起 CVI 显著变化。
