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马杜赖一家三级医院关于呼吸道以外部位洋葱伯克霍尔德菌感染的大型病例系列研究

Burkholderia cepacia infections at sites other than the respiratory tract: A large case series from a tertiary hospital in Madurai.

作者信息

Vithiya G, Raja S

机构信息

Department of Microbiology, Velammal Medical College Hospital and Research Institute, Madurai, India.

Department of Microbiology, AIIMS, Bibinagar, Telengana, India.

出版信息

Indian J Med Microbiol. 2023 Sep-Oct;45:100375. doi: 10.1016/j.ijmmb.2023.100375. Epub 2023 May 23.

Abstract

Sparsely reported extrapulmonary Burkholderia cepacia complex (Bcc) infections highlights the importance of this study. This was a retrospective chart review of 37 patients with extrapulmonary Bcc infections admitted between December 2019 and July 2022 in a tertiary hospital. Males accounted for 70% of cases. 78% had atleast one underlying comorbid illness. Among 37 isolates, 22 were from blood, others include exudates, urine and peritoneal fluid. Susceptibility rates of ceftazidime, meropenem, minocycline, cotrimoxazole and levofloxacin were 88, 88, 70, 65.7 and 56.7% respectively. Eleven died of septic shock and 24 patients (64.8%) had good outcomes, while two were lost to followup.

摘要

关于肺外洋葱伯克霍尔德菌复合体(Bcc)感染的报道较少,凸显了本研究的重要性。这是一项对2019年12月至2022年7月期间在一家三级医院住院的37例肺外Bcc感染患者进行的回顾性病历审查。男性占病例的70%。78%的患者至少有一种基础合并症。在37株分离菌株中,22株来自血液,其他包括渗出液、尿液和腹腔液。头孢他啶、美罗培南、米诺环素、复方新诺明和左氧氟沙星的药敏率分别为88%、88%、70%、65.7%和56.7%。11例死于感染性休克,24例患者(64.8%)预后良好,2例失访。

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