Altern Ther Health Med. 2023 Nov;29(8):271-277.
The purpose of this study was to investigate the effects of warming needle therapy on eosinophils, specific immunoglobulin E (IgE), inflammatory factors, and T lymphocyte subsets in patients with lung qi deficiency and cold-type allergic rhinitis (AR).
A total of 155 patients with lung qi deficiency and cold-type AR from May 2021 to December 2022 were randomly divided into a study group of 76 cases and a control group of 79 cases. The control group received medication (chlorpheniramine and fluticasone), and the study group received medication combined with warming needle therapy. The efficacy, TCM syndrome score, eosinophils, IgE, inflammatory factors (interleukin-6 (IL-6), IL-8, and tumor necrosis factor-alpha (TNF-α)), T lymphocyte subsets (CD3+, CD4+, and CD8+), and rhinoconjunctivitis quality of life questionnaire (RQLQ) scores were evaluated after 2 weeks of treatment.
The total effective rate in the study group was 92.11%, which was higher than that in the control group (77.22%) (P < .05). The TCM syndrome scores of the study group were lower than those of the control group after 1 and 2 weeks of treatment (P < .05). The positive rate of eosinophils in the study group was lower than that in the control group after 1 week (47.37% vs. 64.56%, P < .05) and after 2 weeks (21.05% vs. 37.97%, P < .05) of treatment. The serum levels of specific IgE, IL-6, IL-8, and TNF-α in the study group were lower than those in the control group after 1 and 2 weeks of treatment (P < .05). The peripheral blood levels of CD3+ and CD4+ were higher and the peripheral blood level of CD8+ was lower in the study group than in the control group after 1 and 2 weeks of treatment (P < .05). The RQLQ scores of the study group were lower than those of the control group after 1 and 2 weeks of treatment (P < .05).
Warming needle therapy can effectively improve the clinical symptoms of patients with lung qi deficiency and cold-type AR, reduce inflammation, and enhance immune function.
本研究旨在探讨温针灸疗法对肺气虚寒型变应性鼻炎（AR）患者嗜酸性粒细胞、特异性免疫球蛋白 E（IgE）、炎症因子及 T 淋巴细胞亚群的影响。
选取 2021 年 5 月至 2022 年 12 月收治的肺气虚寒型 AR 患者 155 例，随机分为观察组 76 例和对照组 79 例。对照组采用氯苯那敏联合氟替卡松治疗，观察组在对照组基础上加用温针灸治疗。两组均治疗 2 周后，观察临床疗效，中医证候积分，嗜酸性粒细胞、IgE、炎症因子（白细胞介素-6（IL-6）、IL-8、肿瘤坏死因子-α（TNF-α）），T 淋巴细胞亚群（CD3+、CD4+、CD8+），变应性鼻炎生活质量问卷（RQLQ）评分。
观察组总有效率为 92.11%，高于对照组的 77.22%（P<0.05）。观察组治疗 1、2 周后中医证候积分均低于对照组（P<0.05）。观察组治疗 1 周后嗜酸性粒细胞阳性率低于对照组（47.37%比 64.56%，P<0.05），治疗 2 周后低于对照组（21.05%比 37.97%，P<0.05）。观察组治疗 1、2 周后血清特异性 IgE、IL-6、IL-8、TNF-α水平均低于对照组（P<0.05）。观察组治疗 1、2 周后外周血 CD3+、CD4+水平高于对照组，CD8+水平低于对照组（P<0.05）。观察组治疗 1、2 周后 RQLQ 评分均低于对照组（P<0.05）。
温针灸疗法能有效改善肺气虚寒型 AR 患者的临床症状，减轻炎症反应，增强免疫功能。
