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呼吸机相关障碍的中西医学临床研究探讨。

Investigation of the Clinical Studies of Traditional Chinese Medicine and Western Medicine in the Treatment of Disorders Related to Ventilators.

出版信息

Altern Ther Health Med. 2023 Nov;29(8):286-291.

Abstract

OBJECTIVE

To observe the comprehensive treatment effect of Traditional Chinese Medicine on ventilator-related diseases.

METHODS

From January 2021 to August 2022, a total of 80 patients with ventilator-associated pneumonia were selected and divided into a test group and a matched control group based on the random number table, with 40 cases in each group. The control group received traditional Western medical care, and all patients were given tigecycline intravenously. The patients in the test group were treated with integrated traditional Chinese and Western medicine, and all patients were given tigecycline for injection by intravenous drip combined with Qingfei Huatan decoction orally. The two groups' therapeutic outcomes were contrasted, namely: procalcitonin (PCT), tumor necrosis factor (TNF)-α, hypersensitive C-reactive protein (CRP), blood oxygen saturation (PaO2), and white blood cell (WBC) count. Acute physiology and persistent health scores, clinical lung infection score, mechanical ventilation time, body temperature recovery time, and hospitalization time were recorded.

RESULTS

The effective Of cure in the test group was 37/40 (92.50%) and in the control group it was 30/40 (75.00%). The test group outperformed the control group by a considerable margin (P < .05). The levels of PCT, TNF-α, and hs-CRP were lower in the two groups, and the levels of TNF-α, PCT, and hs-CRP reduced with treatment (P < .05). The white blood cell and PaO2 levels were lower in the experimental group. APACHE II and CPIS scores decreased (P < .05). two groups,Postoperative body temperature recovery time, mechanical ventilation time, and hospital stay were all shortened (P < .05).

CONCLUSION

The combination of traditional Chinese medicine and Western medicine has a positive clinical impact on ventilator-related diseases.

摘要

目的

观察中药综合治疗对呼吸机相关性疾病的疗效。

方法

选取 2021 年 1 月至 2022 年 8 月期间的 80 例呼吸机相关性肺炎患者,根据随机数字表法分为试验组和对照组,每组 40 例。对照组采用西医常规护理,所有患者均给予替加环素静脉滴注。试验组采用中西医结合治疗,所有患者均给予替加环素静脉滴注联合清肺化痰汤口服。对比两组患者的治疗效果,即降钙素原(PCT)、肿瘤坏死因子(TNF)-α、超敏 C 反应蛋白(hs-CRP)、血氧饱和度(PaO2)、白细胞(WBC)计数。记录急性生理与慢性健康评分(APACHEⅡ评分)、临床肺部感染评分(CPIS)、机械通气时间、体温恢复时间、住院时间。

结果

试验组的治愈有效率为 37/40(92.50%),对照组为 30/40(75.00%),试验组明显优于对照组(P <.05)。两组 PCT、TNF-α、hs-CRP 水平均降低,治疗后降低更为明显(P <.05)。试验组白细胞计数和 PaO2 水平更低,APACHEⅡ评分和 CPIS 评分降低(P <.05)。两组术后体温恢复时间、机械通气时间、住院时间均缩短(P <.05)。

结论

中药联合西医治疗对呼吸机相关性疾病有积极的临床影响。

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