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绝经与青少年母亲自杀意念的关联:基于人群队列的纵向研究。

Association between menopause and suicidal ideation in mothers of adolescents: A longitudinal study using data from a population-based cohort.

机构信息

Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands; Department of Psychiatric Nursing, Tohoku University Graduate School of Medicine, Miyagi, Japan; Mental Health Promotion Unit, Research Center for Social Science & Medicine, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.

Mental Health Promotion Unit, Research Center for Social Science & Medicine, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.

出版信息

J Affect Disord. 2023 Nov 1;340:529-534. doi: 10.1016/j.jad.2023.08.055. Epub 2023 Aug 16.

DOI:10.1016/j.jad.2023.08.055
PMID:37573891
Abstract

BACKGROUND

Midlife suicide among women has attracted increasing research attention. This study aimed to investigate the longitudinal association between menopause and suicidal ideation among middle-aged women.

METHODS

Our data were derived from the Tokyo Teen Cohort, a population-based survey of early adolescents (N = 3171) and their primary caregivers (typically, mothers) in Japan. A total of 2944 mothers (baseline mean age = 44.0 years) were included in the analysis. The baseline assessment in this study was performed at second-wave survey from July 2014 to January 2017. A follow-up assessment was conducted at fourth-wave survey from February 2019 to September 2021. Suicidal ideation at baseline and follow-up was assessed using the Suicidal Ideation subscale of the 28-item General Health Questionnaire. Menopausal stage was classified based on self-report at fourth-wave survey.

RESULTS

Participants who started the perimenopausal stage after baseline were significantly more likely to have suicidal ideation at follow-up than those who did not have experienced menopausal transition yet. Participants with greater social support were less likely to report suicidal ideation at follow-up, even after adjusting for baseline suicidal ideation.

LIMITATIONS

This study was based on self-report regarding menopausal stage and only included mothers of adolescents from Japan. An exact length of time from the onset to the presence of suicidal ideation was unavailable.

CONCLUSIONS

Women who have experienced the onset of menopausal transition presented an increased risk of suicidal ideation. Psychosocial interventions to increase social support may be beneficial in preventing mental health inequalities during menopausal transitions.

摘要

背景

女性中年自杀问题引起了越来越多的研究关注。本研究旨在探讨女性更年期与自杀意念之间的纵向关联。

方法

我们的数据来自于东京青少年队列研究,这是一项针对日本早期青少年(N=3171)及其主要照顾者(通常是母亲)的基于人群的调查。共有 2944 名母亲(基线平均年龄为 44.0 岁)纳入分析。本研究的基线评估于 2014 年 7 月至 2017 年 1 月进行的第二波调查中进行。随访评估于 2019 年 2 月至 2021 年 9 月进行的第四波调查中进行。基线和随访时的自杀意念采用 28 项一般健康问卷的自杀意念分量表进行评估。根据第四波调查中的自我报告,将更年期阶段进行分类。

结果

与尚未经历更年期过渡的参与者相比,基线后进入围绝经期的参与者在随访时更有可能出现自杀意念。即使调整了基线自杀意念,社会支持程度较高的参与者报告自杀意念的可能性也较低。

局限性

本研究基于自我报告的更年期阶段,仅包括来自日本的青少年的母亲。从更年期开始到出现自杀意念的确切时间长度不可用。

结论

经历更年期过渡开始的女性出现自杀意念的风险增加。增加社会支持的心理社会干预可能有助于预防更年期过渡期间的心理健康不平等。

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