Schryver H F, Millis D L, Soderholm L V, Williams J, Hintz H F
Cornell Vet. 1986 Oct;76(4):354-60.
The effect of dietary aluminum on the absorption, retention and pathways of excretion of calcium, phosphorus, magnesium, zinc, iron and copper was studied in balance trials in mature ponies in a three by three latin square experiment. A basal diet consisting of one third each of oats, beet pulp and a commercial pelleted, complete horse ration and containing 336 ppm aluminum was supplemented with AlC1(3) . 6H2O. The middle and high level aluminum diets contained 1370 and 4500 ppm aluminum respectively. There was little difference in effect between the middle level aluminum and basal diets. The ponies were in negative phosphorus balance when fed the high level aluminum diet because phosphorus absorption was suppressed. Calcium absorption was unaffected by aluminum intake but the ponies were in negative calcium balance when fed the high aluminum diet due to the greater urinary excretion of calcium by the ponies. Presumably, calcium was excreted in urine because it was not utilized in the formation of bone crystal due to the lack of phosphate. Plasma calcium was elevated and plasma phosphorus was depressed when ponies were fed the high aluminum diet. Plasma hydroxyproline concentration was increased suggesting that bone turnover was increased due to aluminum effects on phosphorus and calcium metabolism. Magnesium, zinc, iron and copper metabolism were unaffected by aluminum intake.
在一项三乘三拉丁方实验中，通过平衡试验研究了日粮铝对成年矮种马钙、磷、镁、锌、铁和铜吸收、保留及排泄途径的影响。基础日粮由燕麦、甜菜粕和一种商业颗粒全价马日粮各三分之一组成，含铝量为336 ppm，添加了六水合氯化铝。中等铝水平日粮和高铝水平日粮分别含铝量为1370 ppm和4500 ppm。中等铝水平日粮与基础日粮的效果差异不大。饲喂高铝水平日粮时，矮种马处于负磷平衡，因为磷的吸收受到抑制。钙的吸收不受铝摄入量的影响，但饲喂高铝日粮时，矮种马处于负钙平衡，原因是矮种马尿钙排泄量增加。推测钙通过尿液排泄是因为由于缺乏磷酸盐，它未被用于骨晶体的形成。饲喂高铝日粮时，血浆钙升高，血浆磷降低。血浆羟脯氨酸浓度增加，表明由于铝对磷和钙代谢的影响，骨转换增加。镁、锌、铁和铜的代谢不受铝摄入量的影响。
