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子宫血管异常:管理与治疗概述

Uterine Vascular Anomalies: Management and Treatment Overview.

作者信息

Matsumoto Monica M, Caridi Theresa M

机构信息

Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.

Department of Radiology, University of Alabama-Birmingham, Birmingham, Alabama.

出版信息

Semin Intervent Radiol. 2023 Aug 10;40(4):342-348. doi: 10.1055/s-0043-1770714. eCollection 2023 Aug.

Abstract

Uterine vascular anomalies (UVAs), while rare, can result in severe, life-threatening hemorrhage. An understanding of the presentation and management options for UVAs is important for interventional radiologists to appropriately evaluate and care for these patients. The authors propose a standardized terminology for UVAs to avoid confusion and conflating congenital from acquired vascular lesions, which have a different pathophysiology. Limited high-level evidence and no definitive guidelines for UVA management exist, although endovascular treatment with uterine artery embolization has generally become the first-line approach for symptomatic or persistent UVAs with high technical and clinical success rates. There is also no consensus on the optimal embolization technique; the authors propose an initial approach to first embolize the dominant uterine artery supplying the UVA with gelatin sponge, with the option to embolize the contralateral side at the time of initial embolization if there is persistent supply (avoiding bilateral empiric embolization). Repeat embolization is feasible and recommended in the setting of recurrence, and both clinical and imaging follow-up is important. Ultimately, a multidisciplinary approach with individualized patient management is needed, particularly in the face of a lack of consensus guidelines for the management of symptomatic UVAs.

摘要

子宫血管异常(UVA)虽然罕见,但可导致严重的、危及生命的出血。了解UVA的临床表现和治疗选择对于介入放射科医生正确评估和治疗这些患者非常重要。作者提出了一种UVA的标准化术语,以避免混淆以及将先天性血管病变与后天性血管病变混为一谈,因为它们具有不同的病理生理学。虽然子宫动脉栓塞的血管内治疗总体上已成为有症状或持续性UVA的一线治疗方法,技术和临床成功率较高,但关于UVA治疗的高级别证据有限,且不存在明确的指南。对于最佳栓塞技术也没有共识;作者提出了一种初始方法,即先用明胶海绵栓塞供应UVA的优势子宫动脉,如果有持续供血,可在初始栓塞时选择栓塞对侧(避免双侧经验性栓塞)。在复发情况下,重复栓塞是可行的且推荐进行,临床和影像学随访都很重要。最终,需要一种多学科方法并进行个体化患者管理,尤其是在缺乏有症状UVA管理共识指南的情况下。

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