Lovell Katie, Larkins Michael C, Pasli Melisa, Hutton Adrienne L
East Carolina University Brody School of Medicine Greenville North Carolina USA.
East Carolina Anesthesia Associates Greenville North Carolina USA.
Clin Case Rep. 2023 Aug 11;11(8):e7765. doi: 10.1002/ccr3.7765. eCollection 2023 Aug.
Chromosome 4q Deletion Syndrome (4QDS) is a rare chromosomal deletion that presents with various congenital defects that could affect anesthetic management. We present a patient with known 4QDS who underwent successful general anesthetic induction, tracheal intubation, and subsequently, bilateral quadratus lumborum nerve blocks, during laparoscopic inguinal hernia repair surgery.
Chromosome 4q deletion syndrome (4QDS) is a rare chromosomal deletion with the potential for congenital defects that could affect the anesthetic management of affected patients, specifically with inconsistent reports of possible laryngeal narrowing which could precipitate intubation difficulties. We present a report of a patient with known 4QDS who underwent successful general anesthetic induction and tracheal intubation, followed by subsequent bilateral quadratus lumborum nerve blocks, in the context of laparoscopic inguinal hernia repair surgery. Given the inconsistent presentation of patients with 4QDS reported in the literature, steps were taken to exercise sufficient caution concerning the overall management of this patient per the most recent guidelines for pediatric patients.
4号染色体q臂缺失综合征（4QDS）是一种罕见的染色体缺失疾病，可导致多种先天性缺陷，进而影响麻醉管理。我们报告了一名已知患有4QDS的患者，该患者在腹腔镜腹股沟疝修补手术中成功接受了全身麻醉诱导、气管插管，随后进行了双侧腰方肌神经阻滞。
4号染色体q臂缺失综合征（4QDS）是一种罕见的染色体缺失疾病，可能导致先天性缺陷，从而影响患病患者的麻醉管理，尤其是关于可能存在的喉狭窄的报道并不一致，这可能会导致插管困难。我们报告了一名已知患有4QDS的患者，该患者在腹腔镜腹股沟疝修补手术中成功接受了全身麻醉诱导和气管插管，随后进行了双侧腰方肌神经阻滞。鉴于文献中报道的4QDS患者临床表现不一致，我们根据最新的儿科患者指南，在该患者的整体管理中采取了足够的谨慎措施。
