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以多发性脑脓毒性栓子模拟缺血性中风表现的瓣周脓肿和感染性心内膜炎的罕见病例

A Rare Presentation of Perivalvular Abscess and Infective Valve Endocarditis as Multiple Cerebral Septic Emboli Mimicking Ischemic Stroke.

作者信息

Mandyam Saikiran, Kalluru Pavan Kumar Reddy, Valisekka Sai Sudha, Parghi Devam P

机构信息

Internal Medicine, Southeast Health Medical Center, Dothan, USA.

Internal Medicine, Sri Venkateswara Medical College, Tirupati, IND.

出版信息

Cureus. 2023 Jul 13;15(7):e41806. doi: 10.7759/cureus.41806. eCollection 2023 Jul.

Abstract

The perivalvular cardiac abscess is a severe condition associated with infective endocarditis, leading to significant morbidity and mortality if not diagnosed and managed promptly. Neurological complications, particularly stroke, can occur due to embolic events resulting from cardiac abscesses. A 63-year-old female with end-stage renal disease and multiple comorbidities presented with altered mental status. Imaging revealed acute ischemic infarcts in the frontotemporal lobes, suggesting the embolic phenomenon. Blood cultures grew , and an echocardiogram showed severe aortic valve destruction with perivalvular abscess. Cardiac abscesses can cause severe complications, including tissue destruction, valve damage, and embolic events. Echocardiography is crucial for diagnosis, detecting vegetation, and assessing associated complications. Transthoracic echocardiography is reliable but has limitations, whereas transesophageal echocardiography is highly sensitive. Prompt antibiotic therapy and surgical intervention are crucial for treatment. Early initiation of appropriate antibiotic therapy and surgical intervention is crucial for positive outcomes. The choice of treatment should be individualized based on the patient's specific condition and the medical team's expertise.

摘要

瓣周心脏脓肿是一种与感染性心内膜炎相关的严重病症,如果不及时诊断和处理,会导致显著的发病率和死亡率。由于心脏脓肿引发的栓塞事件,可能会出现神经并发症,尤其是中风。一名63岁患有终末期肾病和多种合并症的女性出现精神状态改变。影像学检查显示额颞叶急性缺血性梗死,提示栓塞现象。血培养结果为……,超声心动图显示严重的主动脉瓣破坏并伴有瓣周脓肿。心脏脓肿可导致严重并发症,包括组织破坏、瓣膜损害和栓塞事件。超声心动图对于诊断、检测赘生物以及评估相关并发症至关重要。经胸超声心动图可靠但有局限性,而经食管超声心动图高度敏感。及时的抗生素治疗和手术干预对于治疗至关重要。尽早开始适当的抗生素治疗和手术干预对于取得良好疗效至关重要。治疗方案应根据患者的具体情况和医疗团队的专业知识进行个体化选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce83/10422861/ede2eb0b21be/cureus-0015-00000041806-i01.jpg

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