Lozares-Cordero Sergio, Ibáñez-Carreras Reyes, García-Barrios Alberto, Castro-Moreno Raquel, González-Rodríguez Andrea, Sánchez-Casi Marta, Campos-Boned Arantxa, Gandía-Martínez Almudena, Antonio Font-Gómez José, Jiménez-Puertas Sara, Villa-Gazulla David, Díez-Chamarro Javier, Hernández-Hernández Mónica, González-Pérez Víctor, Cisneros-Gimeno Ana Isabel
Department of Physics and Radiation Protection, Miguel Servet University Hospital, Zaragoza, Spain.
Department of Radiation Oncology, Miguel Servet University Hospital, Zaragoza, Spain.
J Med Phys. 2023 Apr-Jun;48(2):175-180. doi: 10.4103/jmp.jmp_18_23. Epub 2023 Jun 29.
The study is intended to perform an end-to-end test of the entire intraoperative process using cadaver heads. A simulation of tumor removal was performed, followed by irradiation of the bed and measurement of absorbed doses with radiochromic films.
Low-energy X-ray intraoperative radiotherapy (IORT) was used for irradiation. A computed tomography study was performed at each site and the absorbed doses calculated by the treatment planning system, as well as absorbed doses with radiochromic films, were studied.
The absorbed doses in the organs at risk (OAR) were evaluated in each case, obtaining maximum doses within the tolerance limits. The absorbed doses in the target were verified and the deviations were <1%.
These tests demonstrated that this comprehensive procedure is a reproducible quality assurance tool which allows continuous assessment of the dosimetric and geometric accuracy of clinical brain IORT treatments. Furthermore, the absorbed doses measured in both target and OAR are optimal for these treatments.
本研究旨在使用尸体头部对整个术中过程进行端到端测试。进行了肿瘤切除模拟，随后对手术床进行照射并用放射变色胶片测量吸收剂量。
采用低能X射线术中放射治疗（IORT）进行照射。在每个部位进行计算机断层扫描研究，并研究由治疗计划系统计算的吸收剂量以及放射变色胶片的吸收剂量。
对每种情况下危及器官（OAR）的吸收剂量进行评估，最大剂量在耐受限度内。对靶区的吸收剂量进行了验证，偏差<1%。
这些测试表明，这一综合程序是一种可重复的质量保证工具，可对临床脑部IORT治疗的剂量学和几何精度进行持续评估。此外，靶区和OAR中测量的吸收剂量对于这些治疗是最佳的。
