Fanji Kong, Jianfeng Ye, Li Lai, Xiaolong Yao, Jun Li
Xianning Central Hospital, No.228 Jingui Road, Xianan District, Xianning, 437000, Hubei, China.
Medical School of Jianghan University, Wuhan, 430000, Hubei, China.
Heliyon. 2023 Jul 25;9(8):e18470. doi: 10.1016/j.heliyon.2023.e18470. eCollection 2023 Aug.
To investigate the correlation between vertebrobasilar dolichoectasia (VBD) and posterior cranial fossa (PCF) space.
The medical records and imaging data of patients with VBD and control group were collected from June 2021 to June 2022 in the Third People's Hospital of Hubei Province. All patients with VBD were graded by head and neck CTA. The grading index was divided into two parts, including vertebral artery bifurcation height and offset degree. Taking the healthy adult subjects of matched age as the control group. The linear volume of posterior cranial fossa was measured by median sagittal CTA images. Middle clivus length, transverse diameter of occipital foramen, supraoccipital length, sagittal diameter of posterior cranial fossa and height diameter of posterior cranial fossa was measured. The volume of the PCF was calculated by 3Dslice software. The relationship between VBD and the volume of PCF was analyzed by SPSS23.0.
The height diameter of posterior cranial fossa, sagittal diameter of posterior cranial fossa, transverse diameter of occipital foramen, clival length, supraoccipital length and space volume of PCF were 34.78 ± 3.67 mm, 85.49 ± 4.15 mm, 30.89 ± 3.94 mm, 44.53 ± 5.36 mm, 45.21 ± 6.45 mm, 171.08 ± 15.81 cm in the case group. The linear volume of PCF and space volume of PCF were significantly lower than those in the control group (P < 0.05). Binary logistic regression analysis showed that the independent risk factors of VBD were height diameter of PCF, sagittal diameter of PCF, transverse diameter of occipital foramen, clival length, supraoccipital length and space volume of posterior cranial fossa. According to the classification, the height and diameter of PCF in grade 1 was significantly smaller than that in grade 2 VBD (P < 0.05). Under the standard of BA bifurcation degree, there were significant differences between different grades of VBD patients and age (P < 0.05).
The smaller volume of PCF may leading the greater possibility of VBD. Under the classification of VBD, the older, the longer the course of disease is, the higher degree of VBD classification is.
探讨椎基底动脉延长扩张症（VBD）与后颅窝（PCF）空间的相关性。
收集湖北省第三人民医院2021年6月至2022年6月VBD患者及对照组的病历资料和影像数据。所有VBD患者均通过头颈CTA进行分级。分级指标分为两部分，包括椎动脉分叉高度和偏移程度。以年龄匹配的健康成年受试者作为对照组。通过正中矢状位CTA图像测量后颅窝的线性体积。测量斜坡中部长度、枕骨大孔横径、枕骨长度、后颅窝矢状径和后颅窝高径。采用3Dslice软件计算PCF的体积。运用SPSS23.0分析VBD与PCF体积之间的关系。
病例组后颅窝高径、后颅窝矢状径、枕骨大孔横径、斜坡长度、枕骨长度及PCF空间体积分别为34.78±3.67mm、85.49±4.15mm、30.89±3.94mm、44.53±5.36mm、45.21±6.45mm、171.08±15.81cm³。病例组PCF的线性体积和空间体积均显著低于对照组（P<0.05）。二元逻辑回归分析显示，VBD的独立危险因素为PCF高径、PCF矢状径、枕骨大孔横径、斜坡长度、枕骨长度及后颅窝空间体积。根据分级，1级PCF的高度和直径显著小于2级VBD（P<0.05）。在BA分叉程度标准下，不同分级的VBD患者与年龄之间存在显著差异（P<0.05）。
PCF体积较小可能导致VBD的可能性更大。在VBD分级中，年龄越大、病程越长，VBD分级程度越高。
