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病例报告：一名巨大垂体神经内分泌肿瘤患者在接种新冠病毒疫苗后因垂体卒中出现急性视力丧失。

Case report: Giant pituitary neuroendocrine tumor presented along with acute visual loss due to pituitary apoplexy after receiving COVID-19 vaccination.

作者信息

Tanaka Haku, Nishimura Fumihiko, Nakase Kenta, Yokoyama Shohei, Nakagawa Ichiro, Yamada Shuichi, Tamura Kentaro, Matsuda Ryosuke, Takeshima Yasuhiro, Kotsugi Masashi, Park Young-Soo, Nakase Hiroyuki

机构信息

Department of Neurosurgery, Nara Medical University, Kashihara, Japan.

出版信息

Front Surg. 2023 Jul 27;10:1220098. doi: 10.3389/fsurg.2023.1220098. eCollection 2023.

DOI:10.3389/fsurg.2023.1220098
PMID:37576925
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10413133/
Abstract

OBJECTIVE

A case of giant pituitary neuroendocrine tumor presented along with acute visual loss due to pituitary apoplexy after receiving a COVID-19 vaccination is reported.

CASE PRESENTATION

A 45-year-old man was referred for a giant pituitary tumor with bitemporal hemianopsia. A surgical procedure was planned and then delayed due to the COVID-19 outbreak in Japan, with a Pfizer/BioNTech vaccine administered while awaiting surgery. Three days after the second COVID-19 vaccination the patient noted a progressively worsening headache that caused pituitary apoplexy and then a decrease in vision. Emergency surgery was thus performed.

CONCLUSION

Pituitary apoplexy is a rare and life-threatening complication that may occur after undergoing a COVID-19 vaccination.

摘要

目的

报告1例巨大垂体神经内分泌肿瘤患者，在接种新冠病毒疫苗后因垂体卒中出现急性视力丧失。

病例介绍

一名45岁男性因巨大垂体肿瘤伴双颞侧偏盲前来就诊。计划进行手术，但由于日本爆发新冠疫情而推迟，在等待手术期间接种了辉瑞/生物科技公司的疫苗。在第二次接种新冠疫苗三天后，患者出现头痛逐渐加重，导致垂体卒中，随后视力下降。因此进行了急诊手术。

结论

垂体卒中是一种罕见且危及生命的并发症，可能在接种新冠疫苗后发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6aac/10413133/2650f0502bdc/fsurg-10-1220098-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6aac/10413133/d094d89dfd4a/fsurg-10-1220098-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6aac/10413133/f643fe8d7bec/fsurg-10-1220098-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6aac/10413133/78ba5e093770/fsurg-10-1220098-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6aac/10413133/2650f0502bdc/fsurg-10-1220098-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6aac/10413133/d094d89dfd4a/fsurg-10-1220098-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6aac/10413133/f643fe8d7bec/fsurg-10-1220098-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6aac/10413133/78ba5e093770/fsurg-10-1220098-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6aac/10413133/2650f0502bdc/fsurg-10-1220098-g004.jpg

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Brain Spine. 2022 Mar 28;2:100878. doi: 10.1016/j.bas.2022.100878. eCollection 2022.
3
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