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罗马尼亚的器官移植:挑战与前景。

Organ transplantation in Romania: challenges and perspectives.

作者信息

Bacuşcă Alberto Emanuel, Tinică Grigore, Enache Mihai, Ţărus Andrei, Hanganu Bianca, Gavriluţă Cristina, Ioan Beatrice Gabriela

机构信息

Department of Cardiovascular Surgery, Cardiovascular Diseases Institute, Iasi, Romania.

"Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.

出版信息

Med Pharm Rep. 2023 Jul;96(3):289-297. doi: 10.15386/mpr-2503. Epub 2023 Jul 27.

DOI:10.15386/mpr-2503
PMID:37577014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10419689/
Abstract

INTRODUCTION

The interest in the field of organ transplantation and the first attempts at making experimental transplant interventions in Romania date from the very beginning of the 20th century. Nevertheless, the evolution of the donating activity and of organ transplantation in Romania has been confronted with a certain inconsistency and a lack of resources necessary to the development of the system.

METHOD

The aim of this study is to analyze the dynamics of the transplantation activity in Romania between 2000 and 2020. The study was accomplished through the analysis of available data corresponding to the above-mentioned period, which were published in the database of the National Transplant Agency, Eurostat and the Global Observatory on Donation and Transplantation. The data were processed using the MedCalc Statistical Software, version 14.8.1 (MedCalc Software bvba, Ostend, Belgium; http://www.medcalc.org; 2014).

RESULTS

The activity of donation and organ transplantation in Romania has been maintained at a low level, with a rate of 3.44 donators pmp and a transplantation rate of 12.55 pmp, as reported for the year 2020. Romania remains at a transplantation rate of under 6.6 pmp, despite the considerable increase in the number of patients on the waiting lists, a fact which describes the picture of a relatively weak system, incapable of providing surgical interventions to cover the minimum needs that emerge within a calendar year.

CONCLUSIONS

Our study points to the fact that the transplantation system in Romania is confronted with a major deadlock. Romania holds the last-but-one place in the ranking of countries in the European Union on transplant activity. The major impediment is the donation rate, which continues to be way below the European average, in a society where the awareness of the necessity to donate is very low, bureaucracy is cumbersome and there is a high degree of mistrust in the medical system, where the equipment is lacking and the infrastructure is incapable of providing services adapted to the modern standards.

摘要

引言

对器官移植领域的关注以及罗马尼亚首次进行实验性移植干预的尝试可追溯到20世纪初。然而,罗马尼亚捐赠活动和器官移植的发展一直面临一定的不一致性以及系统发展所需资源的匮乏。

方法

本研究的目的是分析2000年至2020年罗马尼亚移植活动的动态。该研究通过分析上述时期可获取的数据来完成,这些数据发表于国家移植机构数据库、欧盟统计局以及全球捐赠与移植观察站。数据使用MedCalc统计软件14.8.1版本(MedCalc Software bvba,比利时奥斯坦德;http://www.medcalc.org;2014年)进行处理。

结果

罗马尼亚的捐赠和器官移植活动一直维持在较低水平,2020年报告的捐赠率为每百万人口3.44名捐赠者,移植率为每百万人口12.55例。尽管等待名单上的患者数量大幅增加,但罗马尼亚的移植率仍低于每百万人口6.6例,这一事实描绘了一个相对薄弱的系统,无法提供手术干预以满足一历年中出现的最低需求。

结论

我们的研究指出罗马尼亚的移植系统面临重大僵局这一事实。在欧盟国家移植活动排名中,罗马尼亚位居倒数第二。主要障碍是捐赠率,在一个对捐赠必要性的认识非常低、官僚作风繁琐且对医疗系统高度不信任、缺乏设备且基础设施无法提供符合现代标准服务的社会中,捐赠率仍远低于欧洲平均水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3166/10419689/6053a1a6d813/cm-96-289f7.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3166/10419689/6053a1a6d813/cm-96-289f7.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3166/10419689/cf1a7e3eb392/cm-96-289f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3166/10419689/c1649c657629/cm-96-289f3.jpg
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本文引用的文献

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Organ donation in the US and Europe: The supply vs demand imbalance.美国和欧洲的器官捐赠:供需失衡。
Transplant Rev (Orlando). 2021 Apr;35(2):100585. doi: 10.1016/j.trre.2020.100585. Epub 2020 Oct 11.
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Council of Europe Black Sea Area Project: International Cooperation for the Development of Activities Related to Donation and Transplantation of Organs in the Region.欧洲委员会黑海地区项目:该地区器官捐赠与移植相关活动发展的国际合作。
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THE MALFUNCTIONS OF A NATIONAL TRANSPLANTATION SYSTEM: MULTI-LAYERED EXPLANATIONS FROM WITHIN.
一个国家移植系统的功能失调:来自内部的多层次解释。
Rev Med Chir Soc Med Nat Iasi. 2016 Jan-Mar;120(1):62-9.
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OPTN/SRTR 2013 Annual Data Report: heart.OPTN/SRTR 2013 年年度数据报告:心脏。
Am J Transplant. 2015 Jan;15 Suppl 2:1-28. doi: 10.1111/ajt.13199.
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Organ donation and transplantation in migrants: Piedmont reality from 2004 to 2011.移民中的器官捐赠与移植:2004年至2011年皮埃蒙特地区的实际情况
Transplant Proc. 2013 Sep;45(7):2591-3. doi: 10.1016/j.transproceed.2013.07.031.
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Reluctance to donate organs: a survey among medical students.器官捐赠意愿低:一项针对医学生的调查
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