Wang L J, Huang G J, Zhang D W, Zhang R G, Xu P Z, Peng L, He J
Zhonghua Zhong Liu Za Zhi. 1986 Jul;8(4):283-6.
A series of 748 patients with lung cancer as treated by surgery from 1961 to 1984 is reported. Regular lobectomy was done in 445 (74%) patients, bronchoplastic lobectomy in 67 (11.2%), segmental or wedge excision in 15 (2.5%) and pneumonectomy in 74 (12.3%) in which the ratio of left to right pneumonectomy was 2.9:1. Overall resection rate was 80.4% (601/748) and resection mortality was 1.2% (7/601) (death within 30 days of operation). Overall 5 year survival rate was 42% (169/402). The 5 year survival rate was 35.3% for pneumonectomy, 54.1% for bronchoplastic lobectomy, 42.3% for regular lobectomy and 16.7% for segmental or wedge excision. In this analysis, emphasis is laid to the therapeutic validity of the different modes of surgery. Statistical data show that only when the indication of different surgical interventions are strictly adhered to and the reasonable procedures are carried out, could better results be obtained. In surgical treatment of lung cancer, it is an important principle to eradicate the tumor and its metastatic foci as thorough as possible and to conserve the respiratory function as much as possible. Regular lobectomy has now become the "standard" and first choice operation. Pneumonectomy should be reserved for the patients with absolute necessity due to the extent of the lesion, adequate cardiopulmonary function and possibility of a permanent cure. Pneumonectomy is substituted by bronchoplastic lobectomy to a certain degree, preserving more of the lung function and improving the living quality after operation and long term results. Extensive practice of this surgical modality is advised.
报告了1961年至1984年期间接受手术治疗的748例肺癌患者。445例(74%)患者行常规肺叶切除术,67例(11.2%)行支气管成形肺叶切除术,15例(2.5%)行肺段或楔形切除术,74例(12.3%)行全肺切除术,其中左、右全肺切除术的比例为2.9:1。总切除率为80.4%(601/748),切除死亡率为1.2%(7/601)(术后30天内死亡)。总体5年生存率为42%(169/402)。全肺切除术的5年生存率为35.3%,支气管成形肺叶切除术为54.1%,常规肺叶切除术为42.3%,肺段或楔形切除术为16.7%。本分析重点强调了不同手术方式的治疗有效性。统计数据表明,只有严格遵守不同手术干预的适应证并实施合理的手术步骤,才能取得更好的效果。在肺癌的外科治疗中,尽可能彻底地切除肿瘤及其转移灶并尽可能保留呼吸功能是一项重要原则。常规肺叶切除术现已成为“标准”和首选手术。由于病变范围、足够的心肺功能及永久治愈的可能性,全肺切除术应仅用于绝对必要的患者。支气管成形肺叶切除术在一定程度上替代了全肺切除术,保留了更多的肺功能,提高了术后生活质量及远期疗效。建议广泛开展这种手术方式。