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BEST3-Mediated MEKK2/3 Activation: A Novel Therapeutic Target in Aortopathies.

作者信息

Sawada Hisashi, Daugherty Alan

机构信息

Saha Cardiovascular Research Center, Saha Aortic Center, Department of Physiology, University of Kentucky, KY Saha Cardiovascular Research Center (H.S., A.D.), University of Kentucky, Lexington.

Saha Aortic Center (H.S., A.D.), University of Kentucky, Lexington.

出版信息

Circulation. 2023 Aug 15;148(7):607-609. doi: 10.1161/CIRCULATIONAHA.123.065946. Epub 2023 Aug 14.

DOI:10.1161/CIRCULATIONAHA.123.065946
PMID:37579014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10430773/
Abstract
摘要

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2
2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.2022 ACC/AHA 血管疾病诊断与管理指南:美国心脏协会/美国心脏病学会联合临床实践指南委员会的报告。
Circulation. 2022 Dec 13;146(24):e334-e482. doi: 10.1161/CIR.0000000000001106. Epub 2022 Nov 2.
3
The tyrosine kinase inhibitor Bosutinib does not inhibit angiotensin II-induced abdominal aortic aneurysm: Validation of the importance of PDGFR and c-Kit tyrosine kinases by Imatinib.酪氨酸激酶抑制剂博舒替尼不抑制血管紧张素II诱导的腹主动脉瘤:通过伊马替尼验证血小板衍生生长因子受体(PDGFR)和c-Kit酪氨酸激酶的重要性。
Atherosclerosis. 2022 Jan;340:68-69. doi: 10.1016/j.atherosclerosis.2021.12.001. Epub 2021 Dec 4.
4
Lenvatinib halts aortic aneurysm growth by restoring smooth muscle cell contractility.乐伐替尼通过恢复平滑肌细胞收缩性来阻止主动脉瘤生长。
JCI Insight. 2021 Aug 9;6(15):e140364. doi: 10.1172/jci.insight.140364.
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Therapeutic Effect of Rapamycin on Aortic Dissection in Mice.雷帕霉素对小鼠主动脉夹层的治疗作用。
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