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本文引用的文献

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The WHO Global Tuberculosis 2021 Report - not so good news and turning the tide back to End TB.世界卫生组织 2021 年全球结核病报告——不容乐观的消息与遏制结核病蔓延的努力
Int J Infect Dis. 2022 Nov;124 Suppl 1:S26-S29. doi: 10.1016/j.ijid.2022.03.011. Epub 2022 Mar 20.
2
Clinical features of tuberculous pseudoaneurysm and risk factors for mortality.
J Vasc Surg. 2022 May;75(5):1729-1738.e2. doi: 10.1016/j.jvs.2021.10.048. Epub 2021 Nov 14.
3
Cavitary tuberculosis: the gateway of disease transmission.空洞性肺结核:疾病传播的门户。
Lancet Infect Dis. 2020 Jun;20(6):e117-e128. doi: 10.1016/S1473-3099(20)30148-1. Epub 2020 May 5.
4
Rasmussen's pseudoaneurysm- case report.拉斯穆森假性动脉瘤——病例报告
Respir Med Case Rep. 2018 Aug 25;25:150-153. doi: 10.1016/j.rmcr.2018.08.017. eCollection 2018.
5
Drug-Penetration Gradients Associated with Acquired Drug Resistance in Patients with Tuberculosis.与结核病患者获得性耐药相关的药物渗透梯度。
Am J Respir Crit Care Med. 2018 Nov 1;198(9):1208-1219. doi: 10.1164/rccm.201711-2333OC.
6
On Hæmoptysis, Especially When Fatal, in Its Anatomical and Clinical Aspects.论咯血,尤其是致命性咯血的解剖学和临床方面。
Edinb Med J. 1868 Nov;14(5):385-401.
7
Pulmonary Artery Pseudoaneurysms: Clinical Features and CT Findings.肺动脉假性动脉瘤:临床特征与CT表现
AJR Am J Roentgenol. 2017 Jan;208(1):84-91. doi: 10.2214/AJR.16.16312. Epub 2016 Sep 22.
8
Efficacy of tranexamic acid in haemoptysis: A randomized, controlled pilot study.氨甲环酸治疗咯血的疗效:一项随机对照试验性研究。
Pulm Pharmacol Ther. 2016 Oct;40:80-3. doi: 10.1016/j.pupt.2016.07.006. Epub 2016 Jul 25.
9
Airway management of ruptured pulmonary artery "Rasmussen" aneurysm and massive hemoptysis.破裂的肺动脉“拉斯穆森”动脉瘤及大量咯血的气道管理
BMC Res Notes. 2015 Aug 12;8:346. doi: 10.1186/s13104-015-1313-7.
10
Cavitary penetration of levofloxacin among patients with multidrug-resistant tuberculosis.左氧氟沙星在耐多药结核病患者中的空洞穿透情况。
Antimicrob Agents Chemother. 2015;59(6):3149-55. doi: 10.1128/AAC.00379-15. Epub 2015 Mar 16.

一名患有肺结核的青少年出现大量咯血的罕见但危及生命的原因:拉斯穆森动脉瘤。

Rare but life-threatening cause of massive haemoptysis in an adolscent with tuberculosis: Rasmussen's aneurysm.

作者信息

Yu Michelle Wai Ling, Li Albert M, Lai Ming Hei, Chan Kate Ching Ching

机构信息

Department of Paediatrics, Prince of Wales Hospital, Hong Kong, Hong Kong.

Faculty of Medicine, Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

出版信息

BMJ Case Rep. 2023 Aug 14;16(8):e255480. doi: 10.1136/bcr-2023-255480.

DOI:10.1136/bcr-2023-255480
PMID:37580099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10432668/
Abstract

Rasmussen's aneurysm is a rare yet fatal cause of massive haemoptysis in pulmonary tuberculosis. Early identification and timely intervention are of utmost importance to reduce the associated mortality. A girl in early adolescence presented with persistent fever and massive haemoptysis who required intubation and was subsequently confirmed to have tuberculosis. CT pulmonary angiogram showed the presence of pseudoaneurysms in the left upper and lower lobes. The haemoptysis resolved following the embolisation of the culprit's vessel. Residual lung destruction was evident on CT after a 12-month course of antituberculosis therapy. Rasmussen's aneurysm is a significant vascular complication of cavitary tuberculosis and needs to be considered in patients presenting with massive haemoptysis.

摘要

拉斯穆森动脉瘤是肺结核导致大量咯血的一种罕见但致命的病因。早期识别和及时干预对于降低相关死亡率至关重要。一名青春期早期女孩出现持续发热和大量咯血,需要插管,随后被确诊为肺结核。胸部CT血管造影显示左上叶和下叶存在假性动脉瘤。对责任血管进行栓塞后咯血得到缓解。经过12个月的抗结核治疗后,CT显示有明显的残留肺组织破坏。拉斯穆森动脉瘤是空洞型肺结核的一种重要血管并发症,对于出现大量咯血的患者需要考虑这一情况。