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局部用肾上腺素联合利多卡因对腋窝淋巴结清扫术后引流的影响:一项随机对照试验。

Impact of Topical Epinephrine with Xylocaine on Drainage After Axillary Lymph Node Dissection: A Randomized Controlled Trial.

作者信息

Dehariya Prerna, Agarwal Namrata, Yadav Sanjay Kumar, Agarwal Pawan, Sharma Dhananjaya

机构信息

Department of Surgery, NSCB Medical College, Jabalpur, Madhya Pradesh, 482003, India.

出版信息

World J Surg. 2023 Nov;47(11):2761-2766. doi: 10.1007/s00268-023-07139-6. Epub 2023 Aug 15.

DOI:10.1007/s00268-023-07139-6
PMID:37581639
Abstract

INTRODUCTION

We evaluated the impact of topical epinephrine with xylocaine on drainage after axillary lymph node dissection.

METHODS

Fifty-two women were randomized into two groups, epinephrine with xylocaine drainage (ED) and conventional drainage group (CD). The amount of drainage, duration of drainage catheter, incidence of seroma formation and wound infection were noted.

RESULTS

The mean total drainage volume was less in ED group as compared to CD group (195 ml vs. 353 ml; p = .002). Drainage catheter was removed earlier in ED group as compared to CD group (5.07 + / - 0.99 days vs. 6.65 + / - 1.07 days; p = 0.0001). The incidence of seroma and wound infection was similar in two groups.

CONCLUSION

Topical epinephrine with xylocaine after axillary lymph node dissection results in significantly decreased drainage volume and duration of drainage.

摘要

引言

我们评估了含利多卡因的局部肾上腺素对腋窝淋巴结清扫术后引流的影响。

方法

52名女性被随机分为两组,即含肾上腺素的利多卡因引流组(ED)和传统引流组(CD)。记录引流量、引流管留置时间、血清肿形成发生率和伤口感染情况。

结果

与CD组相比,ED组的平均总引流量较少(195毫升对353毫升;p = 0.002)。与CD组相比,ED组引流管拔除时间更早(5.07±0.99天对6.65±1.07天;p = 0.0001)。两组血清肿和伤口感染发生率相似。

结论

腋窝淋巴结清扫术后使用含利多卡因的局部肾上腺素可显著减少引流量和引流时间。

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本文引用的文献

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Effect of quilting on seroma formation in mastectomies: A meta-analysis.缝合对乳房切除术血清肿形成的影响:荟萃分析。
Surg Oncol. 2021 Dec;39:101665. doi: 10.1016/j.suronc.2021.101665. Epub 2021 Sep 21.
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Flap fixation in preventing seroma formation after mastectomy: an updated meta-analysis.皮瓣固定预防乳房切除术后血清肿形成:一项更新的荟萃分析。
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Role of tranexamic acid in axillary lymph node dissection in breast cancer patients.氨甲环酸在乳腺癌患者腋窝淋巴结清扫术中的作用。
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