Department of Ophthalmology, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
Ophthalmic Plast Reconstr Surg. 2024;40(1):49-54. doi: 10.1097/IOP.0000000000002500. Epub 2023 Aug 15.
To describe the efficacy and persistence of injectable calcium hydroxyapatite (CAHY) to correct orbital volume deficit in postenucleation socket syndrome.
An observational study was conducted as a clinical review of all patients in the authors' practice who received injectable CAHY placed in the extraconal and intraconal space to increase orbital volume with a 10-year follow up. The amount of CAHY to be injected was defined according to the degree of orbital volume deficit. Patients previously treated with radiotherapy or with a conjunctival fornix insufficient to accommodate the external prosthesis were excluded. All the patients with at least 10 years of follow up were included in the study.
Thirty-one postenucleation socket syndrome patients received injectable CAHY for orbital volume augmentation, with a 10-year follow up. The mean amount of preoperative relative enophthalmos measured by Hertel's exophthalmometry was 14.16 ± 2.15. An increase in the mean orbital volume of 3.35 ± 0.91 at 6 months and 2.97 ± 1.35 at 10 years was obtained. The mean follow-up was 219 ± 18 months (range, 184-240). Patients demonstrated clinical and cosmetic improvement that was observed to continue for 10 years. The complications were peribulbar ecchymosis, 2 extrusions of the internal prosthesis, and 2 ptosis.
Injectable CAHY provides safe, simple, repeatable, and cost-effective technique to treat volume deficiency in the enophthalmic orbit in the long term. The volume augmentation obtained with this semipermanent filler demonstrated a lasting effect in the orbit with negligible loss of volume at 10 years.
描述注射用羟基磷灰石(CAHY)在眼窝内容物缺失的眼窝再造术治疗中的疗效和持久性。
本研究为回顾性临床研究,对作者所在机构所有接受注射用 CAHY 眶内和眶周注射以增加眶容积的患者进行了分析,随访时间为 10 年。注射 CAHY 的剂量根据眶内容物缺失程度确定。排除了既往接受过放疗或结膜穹窿不足以容纳外部义眼的患者。所有至少随访 10 年的患者均纳入本研究。
31 例眼窝再造术患者因眶内容物缺失接受了注射用 CAHY 治疗,随访时间为 10 年。Hertel 突眼计测量的术前相对眼球内陷平均值为 14.16±2.15。术后 6 个月和 10 年平均眶容积分别增加了 3.35±0.91 和 2.97±1.35。平均随访时间为 219±18 个月(范围为 184-240)。患者的临床和美容效果得到了改善,且这种改善在 10 年内持续存在。并发症包括眶周瘀斑 2 例、内部义眼突出 2 例和上睑下垂 2 例。
注射用 CAHY 是一种安全、简单、可重复且具有成本效益的技术,可长期治疗眼球内陷患者的眶内容物缺失。用这种半永久性填充物增加的眶容积在 10 年内具有持久效果,体积丢失可忽略不计。