Department of Obstetrics and Gynecology, T.H. Chan School of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
Department of Population and Quantitative Health Sciences, Morningside Graduate School of Biomedical Sciences, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
J Womens Health (Larchmt). 2023 Oct;32(10):1111-1119. doi: 10.1089/jwh.2022.0306. Epub 2023 Aug 16.
Depression affects one in seven perinatal individuals and remains underdiagnosed and undertreated. Individuals with a psychiatric history are at an even greater risk of perinatal depression, but it is unclear how their experiences with the depression care pathway may differ from individuals without a psychiatric history. We conducted a secondary analysis evaluating care access and barriers to care in perinatal individuals who screened positive for depression using the Edinburgh Postnatal Depression Scale ( = 280). Data were analyzed from the PRogram in Support of Moms (PRISM) study, a cluster randomized controlled trial of two interventions for perinatal depression. Individuals with no prepregnancy psychiatric history ( = 113), compared with those with a history ( = 167), were less likely to be screened for perinatal depression, and less likely to be offered a therapy referral, although equally likely to attend if referred. When examining how these differences affected outcomes, those without a psychiatric history had 46% lower odds of attending therapy (95% confidence interval [CI]: 0.19-1.55), 79% lower odds of taking medication (95% CI: 0.08-0.54), and 80% lower odds of receiving any depression care (95% CI: 0.08-0.47). Barriers were similar across groups, except for concerns regarding available treatments and beliefs about self-resolution of symptoms, which were more prevalent in individuals without a psychiatric history. Perinatal individuals without a prepregnancy psychiatric history were less likely to be screened, referred, and treated for depression. Differences in screening and referrals resulted in missed opportunities for care, reinforcing the urgent need for universal mental health screening and psychoeducation during the perinatal period. Clinical Trial Registration No.: NCT02935504.
抑郁症影响每七个围产期个体中的一个,并且这种疾病的诊断和治疗不足。有精神病史的个体患围产期抑郁症的风险更高,但尚不清楚他们在抑郁症护理途径方面的经历与没有精神病史的个体有何不同。我们进行了一项二次分析,评估了使用爱丁堡产后抑郁量表(EPDS)筛查出患有抑郁症的围产期个体( = 280)的护理途径的可及性和障碍。该数据来自支持妈妈计划(PRISM)研究,这是一项针对围产期抑郁症的两种干预措施的集群随机对照试验。与有精神病史的个体( = 167)相比,没有孕前精神病史的个体( = 113)进行围产期抑郁症筛查的可能性较小,接受治疗转诊的可能性也较小,尽管如果被转诊,他们同样可能会就诊。当检查这些差异如何影响结果时,没有精神病史的个体接受治疗的可能性低 46%(95%置信区间 [CI]:0.19-1.55),接受药物治疗的可能性低 79%(95% CI:0.08-0.54),接受任何抑郁症护理的可能性低 80%(95% CI:0.08-0.47)。除了对可用治疗方法的担忧和对症状自行缓解的信念外,两组之间的障碍相似,这些担忧和信念在没有精神病史的个体中更为普遍。没有孕前精神病史的围产期个体更不可能因抑郁症而接受筛查、转诊和治疗。筛查和转诊方面的差异导致了错失护理的机会,这进一步强调了在围产期期间普遍进行心理健康筛查和心理教育的迫切需要。临床试验注册号:NCT02935504。