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吗啉衍生物在农用化学品发现和开发中的应用。

Morpholine Derivatives in Agrochemical Discovery and Development.

机构信息

National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang, Guizhou 550025, People's Republic of China.

出版信息

J Agric Food Chem. 2023 Sep 13;71(36):13197-13208. doi: 10.1021/acs.jafc.3c03818. Epub 2023 Aug 15.

Abstract

Derivatives of morpholine are biologically active organic compounds with special structures discovered in multiple drugs. As a result of the terminal pharmacophore of action and extraordinary activity, they attracted fair attention with regard to pesticide innovation and development. Analysis of brief structure-activity relationships and the summarization of the characteristics of pesticides containing morpholine fragments with efficient activity are key steps in the development of novel pesticides. This review primarily overviews morpholine compounds with insecticidal, fungicidal, herbicidal, antiviral, and plant growth regulation properties to provide educational insight for the creation of new morpholine-containing compounds.

摘要

吗啡啉衍生物是一类具有特殊结构的生物活性有机化合物,在多种药物中被发现。由于其末端药效团和卓越的活性,它们在农药创新和发展方面引起了广泛关注。分析简要的构效关系和总结具有高效活性的含吗啡啉片段的农药的特点是开发新型农药的关键步骤。本文主要综述了具有杀虫、杀菌、除草、抗病毒和植物生长调节活性的吗啡啉类化合物,为新型含吗啡啉类化合物的创制提供了教育启示。

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