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胃癌术中放疗

Intra-operative radiotherapy for carcinoma of the stomach.

作者信息

Takahashi M, Abe M

出版信息

Eur J Surg Oncol. 1986 Sep;12(3):247-50.

PMID:3758361
Abstract

Intra-operative radiotherapy (IOR) was performed for the treatment of 101 patients with gastric cancer. Doses of 28 to 35 Gy with electron beams were delivered during the surgical procedure to tumour beds, high risk lymphnodes and/or remaining cancer nests after gastrectomy. Five-year survival rates were 87.2% for patients with Stage I disease, 83.5% for Stage II, 62.3% for Stage III and 14.7% for Stage IV. Compared with the data on 110 patients treated by surgery alone, IOR has yielded better results in patients with locally advanced disease. Based on these results, indications of IOR for gastric cancer were discussed.

摘要

对101例胃癌患者实施了术中放疗(IOR)。在手术过程中,使用电子束对肿瘤床、高危淋巴结和/或胃切除术后残留的癌巢给予28至35 Gy的剂量。I期疾病患者的5年生存率为87.2%,II期为83.5%,III期为62.3%,IV期为14.7%。与110例仅接受手术治疗的患者的数据相比,术中放疗在局部晚期疾病患者中取得了更好的效果。基于这些结果,对胃癌术中放疗的适应证进行了讨论。

相似文献

1
Intra-operative radiotherapy for carcinoma of the stomach.胃癌术中放疗
Eur J Surg Oncol. 1986 Sep;12(3):247-50.
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[Intraoperative radiotherapy for locally advanced refractory cancer].
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[Radiotherapy for carcinoma of digestive organs].[消化系统器官癌的放射治疗]
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Intraoperative radiotherapy combined with adjuvant chemoradiotherapy for locally advanced gastric adenocarcinoma.术中放疗联合辅助放化疗治疗局部晚期胃腺癌。
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[Pre- and intraoperative radiotherapy for locally advanced gastric cancer in conjunction with extended lymph node dissection: results of phase II clinical study].局部进展期胃癌术前及术中放疗联合扩大淋巴结清扫:II期临床研究结果
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Disease control, survival, and functional outcome after multimodal treatment for advanced-stage tongue base cancer.晚期舌根癌多模式治疗后的疾病控制、生存率及功能转归
Head Neck. 2004 Jul;26(7):561-72. doi: 10.1002/hed.20012.
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[Postoperative radio-chemotherapy in locally advanced gastric cancer].[局部进展期胃癌的术后放化疗]
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引用本文的文献

1
Trends in the surgical treatment of gastric adenocarcinoma.胃腺癌的手术治疗趋势。
Ann Surg Oncol. 2014 Feb;21(2):569-74. doi: 10.1245/s10434-013-3314-x. Epub 2013 Oct 29.
2
Updated analysis of SWOG-directed intergroup study 0116: a phase III trial of adjuvant radiochemotherapy versus observation after curative gastric cancer resection.SWOG 指导的分组研究 0116 的更新分析:辅助放化疗与根治性胃癌切除术后观察的 III 期临床试验。
J Clin Oncol. 2012 Jul 1;30(19):2327-33. doi: 10.1200/JCO.2011.36.7136. Epub 2012 May 14.
3
Localized gastric or gastroesophageal cancer - chemoradiation is a pertinent component of adjuvant treatment for patients at high risk of relapse.
局部胃癌或胃食管癌——对于复发风险高的患者,放化疗是辅助治疗的一个相关组成部分。
Gastrointest Cancer Res. 2009 Mar;3(2 Suppl):S26-32.
4
Management of gastric adenocarcinoma.胃腺癌的管理
Clin Transl Oncol. 2007 Jul;9(7):438-42. doi: 10.1007/s12094-007-0082-8.
5
Role of radiation therapy in gastric adenocarcinoma.放射治疗在胃腺癌中的作用。
World J Gastroenterol. 2006 Mar 14;12(10):1511-20. doi: 10.3748/wjg.v12.i10.1511.
6
Preoperative chemotherapy for unresectable gastric cancer.
World J Surg. 1995 Mar-Apr;19(2):210-5. doi: 10.1007/BF00308628.
7
External beam plus intraoperative irradiation for gastrointestinal cancers.
World J Surg. 1995 Mar-Apr;19(2):191-7. doi: 10.1007/BF00308625.