Yuan Jianqin, Tang Zhongwei, Shi Zongyong, Li Mao, Tang Ruimin
College of Life Sciences, Shanxi Agricultural University, Taigu 030801, Shanxi, China.
Crop Ecological Environment Safety Supervision and Inspection Testing Center (Taiyuan), Ministry of Agriculture and Rural Affairs, Taigu 030801, Shanxi, China.
Sheng Wu Gong Cheng Xue Bao. 2023 Jul 25;39(7):3037-3048. doi: 10.13345/j.cjb.221014.
Protein Engineering is a core compulsory course of biotechnology major, which is the first-class undergraduate major being constructed in Shanxi Province. In view of the problems of single teaching mode of Protein Engineering, such as insufficient students' participation, short teaching time, and expensive experiment cost, the course team carried out the reform and practice of teaching mode for this course, and put forward a new teaching strategy. Under the guidance of the "Golden Course" standard for advancement, innovation and challenge, the course team developed the materials for massive open online courses (MOOC), and carried out the online and offline mixed teaching of Protein Engineering based on BOPPPS+flipped classroom by using the Chao-Xing Fan-Ya network teaching platform. Through this, a comprehensive, systematic and dynamic new teaching system of Protein Engineering was developed. Using the teaching mode based on BOPPPS+flipped classroom, the offline classroom teaching was combined with students' online self-study and homework completion, chapter test and discussion, and this mixed teaching mode was fully integrated into the flipped classroom. After three rounds of teaching practice, the course team had developed a complete, reproducible, scientific and reasonable online and offline mixed teaching mode, which included course materials preparation, exploring experiment guidance, classroom discussion design and course performance evaluation. The online and offline mixed teaching mode of Protein Engineering based on BOPPPS+flipped classroom was helpful for students to improve their autonomous learning ability, to be deeply engaged in the whole teaching process, and to develop a comprehensive and profound understanding of Protein Engineering. This teaching mode improved the teaching quality of Protein Engineering, and facilitated students to learn other follow-up professional courses. Moreover, it provides a reference for the course teaching reform.
《蛋白质工程》是生物技术专业的一门核心必修课，生物技术专业是山西省正在建设的一流本科专业。针对《蛋白质工程》课程教学模式单一，存在学生参与度不足、教学时间短、实验成本高等问题，课程团队对该课程的教学模式进行了改革与实践，提出了新的教学策略。在高阶性、创新性、挑战度“金课”标准的指导下，课程团队开发了大规模在线开放课程（MOOC）资源，并利用超星泛雅网络教学平台开展基于BOPPPS+翻转课堂的《蛋白质工程》线上线下混合式教学。由此，构建了一个全面、系统、动态的《蛋白质工程》课程新教学体系。采用基于BOPPPS+翻转课堂的教学模式，将线下课堂教学与学生线上自主学习及作业完成、章节测试与讨论相结合，这种混合式教学模式充分融入翻转课堂。经过三轮教学实践，课程团队构建了一套完整、可复制、科学合理的线上线下混合式教学模式，包括课程资源准备、探究性实验指导、课堂讨论设计及课程成绩评价等。基于BOPPPS+翻转课堂的《蛋白质工程》线上线下混合式教学模式有助于学生提高自主学习能力，深度参与整个教学过程，对《蛋白质工程》形成全面而深刻的理解。该教学模式提高了《蛋白质工程》的教学质量，有利于学生学习后续其他专业课程。此外，为课程教学改革提供了参考。
