物种基因多样性：来自公开基因组序列分析的启示。
Diversity of genes in species: insights from genome analysis of publicly available genome sequences.
机构信息
Department of Microbiology and Infectious Disease, Toho University School of Medicine , Tokyo, Japan.
出版信息
Antimicrob Agents Chemother. 2023 Sep 19;67(9):e0067323. doi: 10.1128/aac.00673-23. Epub 2023 Aug 16.
Abstract
L1 metallo-β-lactamases produced by exhibit high diversity. Here, we characterized the genomes of species harboring genes using publicly available genome sequences. Our findings provide evidence that species with genes constitute a complex comprising many species with high genetic diversity, and similarities between genes are lower than those of the genome. This suggests that the diversity of is attributable to species diversity in species harboring and the rapid evolutionary changes in genes.
摘要
产生的 L1 金属β-内酰胺酶具有高度多样性。在这里，我们使用公开可用的基因组序列对携带基因的物种的基因组进行了特征描述。我们的研究结果表明，携带基因的物种构成了一个包含许多具有高度遗传多样性的物种的复杂群体，并且基因之间的相似性低于基因组之间的相似性。这表明，携带基因的物种的多样性是由于携带基因的物种的多样性以及基因的快速进化变化所致。
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