Mandorla S, Narducci P L, Bracalente B, Pagliacci M
G Ital Cardiol. 1986 Jun;16(6):487-95.
The anatomy and the cardiac growth in normal fetal heart was studied by real-time-directed M-mode ultrasound from the 19th gestation week until term. A correct fetal cardiac M-mode recording was obtained in 94 out of 144 women (65%). Echocardiographic variables were plotted against gestational age and respective correlation coefficients were determined by linear regression analysis. A comparison between the variables was studied by paired t-test. Left ventricular, right ventricular, left atrial and right atrial chamber size, interventricular septum thickness, right and left wall thickness, aortic and pulmonary diameter all increased linearly with age. Right ventricle (10.1 +/- 3.1) was slightly larger than left ventricle (9.2 +/- 2.8 mm) (p less than 0.001), the pulmonary artery (7.9 +/- 1.9 mm) was greater than the aorta (7.6 +/- 2 mm) (p less than 0.001), while no significant difference was noted between left atrium (10.8 +/- 3.5 mm) and right atrium (10.1 +/- 2.6 mm), right ventricular wall thickness (2.7 +/- 0.9 mm) and left ventricular wall thickness (3.0 +/- 1.1 mm). The ratios of left ventricular/right ventricular diameter, left atrial/right atrial and left atrial/aortic diameters, the relative wall thickness and arterial vessels diameters did not change significantly throughout the pregnancy. The ratio interventricular septum/posterior wall thickness was 1.14 +/- 0.36 and ratio of 1.5 or greater was found in 14.5% of the fetal normal heart. The ratio left atrial/aortic diameter was 1.32 +/- 0.21 and left atrium was significantly greater than aorta (p less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)
从妊娠第19周直至足月,采用实时引导M型超声对正常胎儿心脏的解剖结构及心脏生长情况进行了研究。144名孕妇中有94名(65%)获得了正确的胎儿心脏M型记录。将超声心动图变量与孕周进行绘图,并通过线性回归分析确定各自的相关系数。采用配对t检验对变量进行比较。左心室、右心室、左心房和右心房的腔径、室间隔厚度、右心室和左心室壁厚度、主动脉和肺动脉直径均随孕周线性增加。右心室(10.1±3.1)略大于左心室(9.2±2.8mm)(p<0.001),肺动脉(7.9±1.9mm)大于主动脉(7.6±2mm)(p<0.001),而左心房(10.8±3.5mm)与右心房(10.1±2.6mm)、右心室壁厚度(2.7±0.9mm)与左心室壁厚度(3.0±1.1mm)之间无显著差异。左心室/右心室直径比、左心房/右心房直径比、左心房/主动脉直径比、相对壁厚度和动脉血管直径在整个孕期均无显著变化。室间隔/后壁厚度比为1.14±0.36,14.5%的正常胎儿心脏该比值≥1.5。左心房/主动脉直径比为1.32±0.21,左心房明显大于主动脉(p<0.001)。(摘要截断于250字)