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急性髓系白血病的表现可能更糟吗？“同时发生多血管血栓形成的罕见病因”。

Could Acute Myeloid Leukemia Have Presented Even Worse? "Uncommon Cause of Concurrently Multivessel Thrombosis".

机构信息

Izmir Tepecik Training and Research Hospital - Cardiology, Izmir - Turquia.

Izmir Tepecik Training and Research Hospital - Internal Medicine, Izmir - Turquia.

出版信息

Arq Bras Cardiol. 2023 Jul;120(8):20220808. doi: 10.36660/abc.20220808.

DOI:10.36660/abc.20220808
PMID:37586004
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10464858/
Abstract

Acute promyelocytic leukemia (APL) is a subgroup of acute myeloid leukemia (AML). Although it is known that hemorrhagic complications are common, thrombotic complications are not as rare as thought. However, myocardial infarction and ischemic stroke incidence are very rare during AML. Here, we present the astonishing case of APL diagnosed with pancytopenia in its presentation with acute myocardial infarction and ischemic stroke.

摘要

急性早幼粒细胞白血病（APL）是急性髓系白血病（AML）的一个亚型。虽然已知出血并发症很常见，但血栓并发症并不像人们想象的那么罕见。然而，在 AML 期间心肌梗死和缺血性中风的发生率非常罕见。在这里，我们报告了一个令人惊讶的病例，即表现为全血细胞减少的 APL 合并急性心肌梗死和缺血性中风。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/fc2807ccf517/0066-782X-abc-120-08-e20220808-gf05-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/5374f8a660be/0066-782X-abc-120-08-e20220808-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/a4827c927fe7/0066-782X-abc-120-08-e20220808-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/1ea56a4bec39/0066-782X-abc-120-08-e20220808-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/db5939dcc75d/0066-782X-abc-120-08-e20220808-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/db047be640a8/0066-782X-abc-120-08-e20220808-gf05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/5374f8a660be/0066-782X-abc-120-08-e20220808-gf01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/a4827c927fe7/0066-782X-abc-120-08-e20220808-gf02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/1ea56a4bec39/0066-782X-abc-120-08-e20220808-gf03-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/0a27373526dd/0066-782X-abc-120-08-e20220808-gf04-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/fc2807ccf517/0066-782X-abc-120-08-e20220808-gf05-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/5374f8a660be/0066-782X-abc-120-08-e20220808-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/a4827c927fe7/0066-782X-abc-120-08-e20220808-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/1ea56a4bec39/0066-782X-abc-120-08-e20220808-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/db5939dcc75d/0066-782X-abc-120-08-e20220808-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/db047be640a8/0066-782X-abc-120-08-e20220808-gf05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/5374f8a660be/0066-782X-abc-120-08-e20220808-gf01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/a4827c927fe7/0066-782X-abc-120-08-e20220808-gf02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/1ea56a4bec39/0066-782X-abc-120-08-e20220808-gf03-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/0a27373526dd/0066-782X-abc-120-08-e20220808-gf04-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d8b/10464858/fc2807ccf517/0066-782X-abc-120-08-e20220808-gf05-en.jpg

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Thromb Res. 2022 Feb;210:33-41. doi: 10.1016/j.thromres.2021.12.020. Epub 2021 Dec 29.
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Acute promyelocytic leukemia presenting as recurrent venous and arterial thrombotic events: a case report and review of the literature.以复发性静脉和动脉血栓形成事件为表现的急性早幼粒细胞白血病：一例报告并文献复习
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Acute Promyelocytic Leukemia Presenting as Bilateral Acute Limb Ischemia and ST Elevation Myocardial Infarction: A Case Report.以双侧急性肢体缺血和ST段抬高型心肌梗死为表现的急性早幼粒细胞白血病：一例报告
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Stroke Rate Increases Around the Time of Cancer Diagnosis.癌症诊断前后中风发生率增加。
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