Assistant Professor, Department of Nursing, Soonchunhyang University, Cheonan, Republic of Korea.
Assistant Professor, College of Nursing, Gachon University, Incheon, Republic of Korea.
Semin Oncol Nurs. 2023 Oct;39(5):151499. doi: 10.1016/j.soncn.2023.151499. Epub 2023 Aug 14.
Chemotherapy-induced peripheral neuropathy is an unpleasant symptom experienced by most cancer survivors who receive neurotoxic chemotherapy. It is not life threatening; however, it impairs sensorimotor skills, thereby interfering with daily activities and reducing the quality of life. Healthcare providers are becoming increasingly aware of the significance of its management. Nonetheless, a lack of understanding remains. This study aimed to understand the experience of cancer survivors with chemotherapy-induced peripheral neuropathy.
The selection and search for relevant literature conformed to the Preferred Reporting Items for Systematic Review and Meta-analysis Protocols guidelines. Four databases were searched for literature exploring the experiences of cancer survivors with chemotherapy-induced peripheral neuropathy. Moreover, articles from reference lists were retrieved. Of 969 collected articles, 13 qualitative studies were included. The seven-step meta-ethnography developed by Noblits and Hare was used to analyze and synthesize selected studies. This study complied with the enhancing transparency in reporting the synthesis of qualitative research guidelines.
Three themes ("Tough and challenging life with chemotherapy-induced peripheral neuropathy," "Being patient in a chaotic life," and "Transition to a new way of life") and six subthemes were derived after reviewing, analyzing, and synthesizing selected study findings. They faced difficult daily challenges and endured psychologically chaotic moments; however, they gradually learned to live with the symptoms and adapted their way of life.
This review emphasizes the importance of the need for personalized nursing interventions promoting self-management and new adaptation strategies for gaining better understanding of chemotherapy-induced peripheral neuropathy.
化疗引起的周围神经病是大多数接受神经毒性化疗的癌症幸存者所经历的一种不愉快的症状。它不会危及生命；然而，它会损害感觉运动技能，从而干扰日常活动并降低生活质量。医疗保健提供者越来越意识到其管理的重要性。尽管如此，仍然存在理解不足的问题。本研究旨在了解癌症幸存者化疗引起的周围神经病的体验。
相关文献的选择和搜索符合系统评价和荟萃分析方案的首选报告项目指南。搜索了四个数据库，以寻找探索癌症幸存者化疗引起的周围神经病体验的文献。此外，还从参考文献中检索了文章。在收集的 969 篇文章中，有 13 篇定性研究被纳入。使用 Noblits 和 Hare 开发的七步元民族志分析和综合选定的研究。本研究符合提高报告定性研究综合透明度的指南。
在审查、分析和综合选定研究结果后，得出了三个主题（“化疗引起的周围神经病的艰难而具有挑战性的生活”、“在混乱的生活中保持耐心”和“过渡到新的生活方式”）和六个亚主题。他们面临着日常挑战的困难，并忍受着心理混乱的时刻；然而，他们逐渐学会了与症状共存并调整自己的生活方式。
本综述强调了需要个性化护理干预以促进自我管理和新的适应策略的重要性，以更好地理解化疗引起的周围神经病。
