Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Trends Cell Biol. 2023 Oct;33(10):817-819. doi: 10.1016/j.tcb.2023.07.010. Epub 2023 Aug 14.
Intestinal epithelial cells form the largest barrier in the body, separating us from the outside world. Here, we review recent findings that highlight the role of autophagy in the cell-intrinsic response of the epithelial cells to the harsh intestinal environment and how they shape host physiology.
肠道上皮细胞构成了人体最大的屏障,将我们与外界环境隔离开来。在这里,我们回顾了最近的发现,这些发现强调了自噬在肠道上皮细胞对恶劣肠道环境的细胞固有反应中的作用,以及它们如何塑造宿主生理学。