Department of Surgery, OLVG West, Amsterdam, the Netherlands.
Department of Surgery/Vitalys Clinic, Rijnstate, Arnhem, the Netherlands.
Surgeon. 2023 Dec;21(6):e361-e366. doi: 10.1016/j.surge.2023.07.002. Epub 2023 Aug 14.
Obstructive sleep apnoea (OSA) is a breathing disorder resulting in blockage of airflow and hypo-oxygenation. The incidence of OSA in patients with class 2 or 3 obesity (Body Mass index, BMI >35) is 60-70%. Unfortunately, most bariatric patients are unaware they suffer from OSA. Untreated OSA can lead to perioperative cardiopulmonary complications. The aim of this study was to identify predictors associated with moderate to severe OSA and asses the incidence of OSA-related complications in a large cohort of patients who underwent OSA-screening and treatment if indicated before bariatric surgery.
All consecutive patients who underwent primary bariatric surgery between September 2013 and September 2019 were included. Univariable and multivariable logistic regression analysis was performed to identify potential predictors for moderate to severe OSA using sleep studies.
A total of 2872 patients who underwent bariatric surgery were included for analysis. Overall, OSA was identified in 62.5% of all patients and moderate to severe OSA (AHI ≥15) in 28.6%. Independent predictors for moderate to severe OSA were male gender (p < 0.001), age (p < 0.001), preoperative BMI (p < 0.001), preoperative waist circumference (p < 0.001), hypertension (p < 0.001), and dyslipidaemia (p = 0.046). The incidence of OSA-related complications was low (0.8%) and not significantly different among the different OSA severity classes.
This is the largest study to assess OSA presence and OSA-related complications in patients undergoing bariatric surgery. The incidence of potential OSA-related complications was low (0.8%). We believe focus could be shifted towards more cost-efficient strategies where OSA screening is omitted such as perioperative continuous monitoring.
阻塞性睡眠呼吸暂停(OSA)是一种呼吸紊乱,导致气流阻塞和低氧血症。2 类或 3 类肥胖(体重指数,BMI>35)患者的 OSA 发生率为 60-70%。不幸的是,大多数肥胖患者并不知道自己患有 OSA。未经治疗的 OSA 可导致围手术期心肺并发症。本研究旨在确定与中重度 OSA 相关的预测因素,并评估在接受肥胖手术前进行 OSA 筛查和治疗的大样本患者中 OSA 相关并发症的发生率。
纳入 2013 年 9 月至 2019 年 9 月期间接受原发性肥胖手术的所有连续患者。使用睡眠研究对单变量和多变量逻辑回归分析进行分析,以确定中重度 OSA 的潜在预测因素。
共纳入 2872 例接受肥胖手术的患者进行分析。总体而言,所有患者中有 62.5%存在 OSA,28.6%存在中重度 OSA(AHI≥15)。中重度 OSA 的独立预测因素为男性(p<0.001)、年龄(p<0.001)、术前 BMI(p<0.001)、术前腰围(p<0.001)、高血压(p<0.001)和血脂异常(p=0.046)。OSA 相关并发症的发生率较低(0.8%),且不同 OSA 严重程度组之间无显著差异。
这是评估接受肥胖手术患者 OSA 存在和 OSA 相关并发症的最大研究。潜在 OSA 相关并发症的发生率较低(0.8%)。我们认为可以将重点转移到更具成本效益的策略上,例如省略 OSA 筛查而采用围手术期连续监测。